使用男性 OPAQ 测量骨质疏松男性的健康相关生活质量 (HRQOL)。
Measuring health-related quality of life (HRQOL) in osteoporotic males using the Male OPAQ.
机构信息
Center for the Study of Aging and Human Development, Duke University Medical Center, Durham, NC, USA.
出版信息
Osteoporos Int. 2012 Mar;23(3):841-52. doi: 10.1007/s00198-011-1625-y. Epub 2011 Apr 29.
UNLABELLED
The Male Osteoporosis Assessment Questionnaire (OPAQ™) is a health-related quality of life (HRQOL) instrument that can differentiate between men with and without fracture. The Male OPAQ™ is a reliable and validated instrument that may be utilized in clinical trials seeking to include male populations.
INTRODUCTION
Men with osteoporosis (OP) experience poorer clinical outcomes than do women with the disorder, but little is known about the impact of OP on men's HRQOL. This study aimed to test the validity, reliability, and ability to differentiate between men with and without fracture of an HRQOL for men with osteoporosis, the Male OPAQ™.
METHODS
The OPAQ and OPAQ-SV were tested for face validity in interviews with male OP patients, and a revised, male-specific instrument was developed. Thirty-seven men ages 50+ completed the Male OPAQ™ and SF-12 at baseline and a two-week retest of the Male OPAQ™. To analyze both the domain and dimension scores, a normalization procedure was performed on the data to determine health status scores from 0 to 100. Descriptive statistics were calculated for each item and site. Reliability and validity of the Male OPAQ™ were assessed using Pearson's r.
RESULTS
The Male OPAQ™ can discriminate between men with and without fracture, and men who have more fractures have poorer scores. Instrument domains correspond to those of the SF-12.
CONCLUSIONS
The Male OPAQ(TM) is a brief and sensitive tool for measuring HRQOL in men with OP. Further testing in a more diverse and large sample is warranted.
非盲法
男性骨质疏松评估问卷（OPAQ）是一种健康相关生活质量（HRQOL）工具，可以区分有和无骨折的男性。男性 OPAQ 是一种可靠且经过验证的工具，可用于临床试验，旨在纳入男性人群。
引言
患有骨质疏松症（OP）的男性比患有该疾病的女性临床结局更差，但对于 OP 对男性 HRQOL 的影响知之甚少。本研究旨在测试男性骨质疏松症 HRQOL 男性 OPAQ 的有效性、可靠性和区分有和无骨折男性的能力。
方法
在对男性 OP 患者的访谈中对 OPAQ 和 OPAQ-SV 进行了表面有效性测试，并开发了一个经过修订的男性专用工具。37 名年龄在 50 岁以上的男性在基线时完成了男性 OPAQ 和 SF-12，并在两周内重新测试了男性 OPAQ。为了分析域和维度评分，对数据进行了归一化处理，以确定从 0 到 100 的健康状况评分。对每个项目和站点计算了描述性统计数据。使用 Pearson r 评估男性 OPAQ 的可靠性和有效性。
结果
男性 OPAQ 可以区分有和无骨折的男性，骨折越多的男性得分越低。仪器域与 SF-12 相对应。
结论
男性 OPAQ（TM）是一种用于测量男性骨质疏松症患者 HRQOL 的简短而敏感的工具。需要在更多样化和更大的样本中进一步测试。
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