Center for Interventional Pain Management, Daejeon Woori Hospital, Daejeon, Korea.
J Korean Med Sci. 2011 May;26(5):637-41. doi: 10.3346/jkms.2011.26.5.637. Epub 2011 Apr 21.
We examined time trend and age-period-cohort effects on acute myocardial infarction (AMI) mortality in Korean adults from 1988 to 2007. Annual AMI mortality data and population statistics from 1988 to 2007 were obtained from the STATISTICS KOREA website. Age adjusted mortality for four 5-yr calendar periods (1988-1992 to 2003-2007) was calculated by direct standardization using the Year 2000 WHO world standard population. A log-linear Poisson regression model was used to estimate age, period, and cohort effects on AMI mortality. In both genders, age-adjusted AMI mortality increased from period one (1988-1992) to period three (1998-2002) but decreased in period four (2003-2007). An exponential age effect was noted in both genders. The rate ratio of the cohort effect increased up to the 1943 birth cohort and decreased gradually thereafter, and the rate ratio of the period effect increased up to period three (1998-2002) and decreased thereafter. Our results suggest that AMI mortality in Korean adults has decreased since the period 1998-2002 and age, period, and cohort effects have influenced on AMI mortality.
我们考察了 1988 年至 2007 年韩国成年人急性心肌梗死（AMI）死亡率的时间趋势和年龄-时期-队列效应。1988 年至 2007 年的 AMI 死亡率年度数据和人口统计数据来自 STATISTICS KOREA 网站。使用 2000 年世卫组织世界标准人口对四个 5 年日历期（1988-1992 年至 2003-2007 年）进行了年龄调整死亡率的直接标准化计算。使用对数线性泊松回归模型估计 AMI 死亡率的年龄、时期和队列效应。在男女两性中，年龄调整后的 AMI 死亡率从第 1 期（1988-1992 年）增加到第 3 期（1998-2002 年），但在第 4 期（2003-2007 年）下降。在两性中均观察到指数年龄效应。队列效应的比率比增加到 1943 年出生队列，此后逐渐下降，而时期效应的比率比增加到第 3 期（1998-2002 年），此后下降。我们的研究结果表明，自 1998-2002 年以来，韩国成年人的 AMI 死亡率有所下降，年龄、时期和队列效应均对 AMI 死亡率产生了影响。
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