韩国 2007 年至 2016 年住院急性心肌梗死患者发病率和病死率趋势。
The Trend in Incidence and Case-fatality of Hospitalized Acute Myocardial Infarction Patients in Korea, 2007 to 2016.
机构信息
Regional Cardiocerebrovascular Disease Center, Gyeongsang National University Hospital, Jinju, Korea.
Center of Biomedical Data Science, Yonsei University Wonju College of Medicine, Wonju, Korea.
出版信息
J Korean Med Sci. 2019 Dec 30;34(50):e322. doi: 10.3346/jkms.2019.34.e322.
BACKGROUND
The trend in the incidence of hospitalized acute myocardial infarction (AMI) and the difference between regions has not been reported in Korea since 2010. Thus, we aimed to inspect recent trends and regional differences in the incidence of AMI and case-fatality between 2007 and 2016.
METHODS
Data from the medical utilization cohort from 2002 to 2016 were analyzed. New incidence of AMI was identified by checking the diagnosis code, duration of admission, type of test, treatment, and medication. Age-standardized incidence rate by gender, age group, and resident region was calculated from 2007 to 2016. Cumulative case-fatality rate was calculated until 3 years.
RESULTS
Age-standardized incidence of hospitalized AMI decreased from 53.6 cases per 100,000 person-years in 2007 to 38.9 cases in 2011. Thereafter, the incidence gradually increased to 43.2 cases in 2016. The trend by gender and age groups was also similar to the total trend. The regional age-standardized incidence was the highest in Daegu (50.3 cases per 100,000 person-years) and the lowest in Sejong (30.2 cases), which were similar to the ischemic heart disease mortality in these regions. The 7-, 30-, and 90-days and 1- and 3-years average case-fatality over 10 years were 3.2%, 6.9%, 9.9%, 14.7%, and 22.4%, respectively.
CONCLUSION
Although case-fatality continuously decreased from 2007 to 2016, hospitalized AMI incidence decreased from 2007 to 2011 and gradually increased from 2011 to 2016, with marked disparity between regions. Effective preventive strategies to decrease AMI incidence are required to decrease cardiovascular disease mortality in Korea.
背景
自 2010 年以来，韩国尚未报告过住院急性心肌梗死（AMI）的发病率趋势和地区差异。因此，我们旨在检查 2007 年至 2016 年期间 AMI 的发病率和病死率的近期趋势和地区差异。
方法
分析了 2002 年至 2016 年的医疗利用队列数据。通过检查诊断代码、住院时间、检查类型、治疗和药物来确定新的 AMI 发生率。根据性别、年龄组和居民地区，从 2007 年至 2016 年计算出年龄标准化发病率。计算直至 3 年的累积病死率。
结果
2007 年住院 AMI 的年龄标准化发病率为 53.6 例/100,000 人年，2011 年降至 38.9 例。此后，发病率逐渐上升至 2016 年的 43.2 例。性别和年龄组的趋势也与总趋势相似。地区年龄标准化发病率在大邱最高（50.3 例/100,000 人年），世宗最低（30.2 例），与这些地区的缺血性心脏病死亡率相似。10 年间 7 天、30 天、90 天和 1 年、3 年的平均病死率分别为 3.2%、6.9%、9.9%、14.7%和 22.4%。
结论
尽管病死率从 2007 年持续下降至 2016 年，但住院 AMI 的发病率从 2007 年至 2011 年下降，从 2011 年至 2016 年逐渐上升，地区之间存在明显差异。需要采取有效的预防策略来降低 AMI 的发病率，以降低韩国的心血管疾病死亡率。
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