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关于梓醇的化学和生物活性的高级研究。

Advanced research on acteoside for chemistry and bioactivities.

作者信息

He Jiang, Hu Xiao-Peng, Zeng Yong, Li Yan, Wu Hai-Qiang, Qiu Rong-Zhu, Ma Wen-Jie, Li Tao, Li Chen-Yang, He Zhen-Dan

机构信息

School of Medicine, College of Life Science, School of Chemistry and Chemical Engineering, Shenzhen University, China.

出版信息

J Asian Nat Prod Res. 2011 May;13(5):449-64. doi: 10.1080/10286020.2011.568940.

DOI:10.1080/10286020.2011.568940
PMID:21534045
Abstract

Acteoside is one kind of phenylethanoid glycoside, which has shown a lot of biological activities. This article reviewed the study progress of acteoside, such as distribution, preparation, identification, and bioactivities.

摘要

毛蕊花糖苷是一种苯乙醇苷类化合物，已显示出多种生物活性。本文综述了毛蕊花糖苷的研究进展，包括其分布、制备、鉴定及生物活性等方面。

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2
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Acteoside and its aglycones protect primary cultures of rat cortical cells from glutamate-induced excitotoxicity.毛蕊花糖苷及其苷元可保护大鼠皮层细胞原代培养物免受谷氨酸诱导的兴奋性毒性作用。
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Inhibition of amyloid β aggregation by acteoside, a phenylethanoid glycoside.苯乙醇苷类化合物毛蕊花糖苷对β-淀粉样蛋白聚集的抑制作用
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引用本文的文献

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Inflammopharmacology. 2025 Jun 23. doi: 10.1007/s10787-025-01811-0.
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Effects of Elicitation on Leaf Callus and Changes in Verbascoside Content.诱导对叶片愈伤组织的影响及毛蕊花糖苷含量的变化
Plants (Basel). 2025 May 4;14(9):1386. doi: 10.3390/plants14091386.
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Distribution, biosynthesis, and synthetic biology of phenylethanoid glycosides in the order Lamiales.唇形目苯乙醇苷类化合物的分布、生物合成及合成生物学
Plant Biotechnol (Tokyo). 2024 Sep 25;41(3):231-241. doi: 10.5511/plantbiotechnology.24.0720a.
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Acteoside relieves diabetic retinopathy through the inhibition of Müller cell reactive hyperplasia by regulating TXNIP and mediating Kir4.1 channels in a PI3K/Akt-dependent manner.毛蕊花糖苷通过以PI3K/Akt依赖性方式调节TXNIP并介导Kir4.1通道来抑制Müller细胞反应性增生，从而缓解糖尿病视网膜病变。
PLoS One. 2024 Dec 17;19(12):e0312565. doi: 10.1371/journal.pone.0312565. eCollection 2024.
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Discrimination of Baphicacanthis Cusiae Rhizoma et radix and its adulterant species and establishment of an assay method for quality control.马蓝根茎及根与其伪品的鉴别及质量控制测定方法的建立。
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Acteoside alleviates UUO-induced inflammation and fibrosis by regulating the HMGN1/TLR4/TREM1 signaling pathway.毛蕊花糖苷通过调控 HMGN1/TLR4/TREM1 信号通路缓解 UUO 诱导的炎症和纤维化。
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