Khan N A, Teli M Ashraf, Mohib-Ul Haq M, Bhat G M, Lone Mohd M, Afroz F
Department of Radiation Oncology, SKIMS, Srinagar, India.
J Cancer Res Ther. 2011 Jan-Mar;7(1):15-8. doi: 10.4103/0973-1482.80431.
BACKGROUND/OBJECTIVE: Esophageal cancer has a peculiar geographical distribution and shows marked differences in incidence within a particular geographical region. Presently, as there seems little prospect of early detection of this cancer, an understanding of the etiological factors may suggest opportunities for its primary prevention. In this paper, we have tried to determine the role of diet and other life-style related factors in the etiology of cancer of esophagus.
A total of 100 confirmed squamous cell carcinoma of esophagus patients were enrolled for the study (Group A). 100 healthy subjects were included as controls (Group B). A predesigned questionnaire dealing with the basic patient data, dietary and smoking habits etc. was distributed among the cases in both groups. The data was thoroughly analyzed to define an association with the development of cancer of esophagus.
Group A patients included 71 males and 29 females in the age range of 40-70 years. Majority 37% were farmers, 29% house wives. Of the 72% smokers, 66% smoked hookah. 29% had positive family history. More than 90% took salt-tea at breakfast. Meat consumption was low, 44% took it weekly and 42% on monthly basis. 69% took fish yearly. Group B included 75 males and 25 females of which 35.7% were hookah smokers.
Poor socio-economic status resulting in fewer intakes of fresh fruits, vegetables and fish in addition to heavy hookah smoking are suspected to be the major risk factors for the development of esophageal cancer.
背景/目的：食管癌具有独特的地理分布，且在特定地理区域内发病率存在显著差异。目前，由于这种癌症早期检测的前景似乎渺茫，了解其病因可能会为一级预防提供机会。在本文中，我们试图确定饮食和其他与生活方式相关的因素在食管癌病因中的作用。
共纳入100例确诊的食管鳞状细胞癌患者进行研究（A组）。纳入100名健康受试者作为对照（B组）。向两组病例发放了一份预先设计的问卷，内容涉及患者基本数据、饮食习惯和吸烟习惯等。对数据进行了全面分析，以确定与食管癌发生的关联。
A组患者包括71名男性和29名女性，年龄在40至70岁之间。大多数（37%）是农民，29%是家庭主妇。在72%的吸烟者中，66%抽水烟。29%有阳性家族史。超过90%的人早餐喝咸茶。肉类摄入量较低，44%的人每周吃一次，42%的人每月吃一次。69%的人每年吃鱼。B组包括75名男性和25名女性，其中35.7%是水烟吸烟者。
社会经济地位低下导致新鲜水果、蔬菜和鱼类摄入量减少，再加上大量抽水烟，被怀疑是食管癌发生的主要危险因素。
