Chaudhary Sandeep, Thomas Vladimir, Todaro Louis, Legendre Onica, Pecic Stevan, Harding Wayne W
Department of Chemistry, Hunter College, City University of New York, New York, NY 10065.
Nat Prod Commun. 2008;3(11):1747-1750.
From an acetone extract of the aerial parts of Tidestromia oblongifolia (Amaranthaceae), a new drimane sesquiterpenoid bearing an 11,12,13-trihydroxydrimene skeleton (1) as well as the 11,12 acetonide of 1 were isolated. Three known stigmastane triterpenoids were also isolated. Structures were elucidated with the aid of 1D and 2D NMR spectroscopic techniques. The absolute configuration of 1 was confirmed by single-crystal x-ray crystallography. This is the first report on phytochemical constituents from any plant of the genus Tidestromia and is the first report of the occurrence of drimanes in the Amaranthaceae.
从长叶碱蓬（苋科）地上部分的丙酮提取物中，分离出一种带有11,12,13 - 三羟基杜松烯骨架的新杜松烷倍半萜（1）以及1的11,12 - 丙酮化物。还分离出三种已知的豆甾烷三萜类化合物。借助一维和二维核磁共振光谱技术阐明了其结构。通过单晶X射线晶体学确定了1的绝对构型。这是关于碱蓬属任何植物的植物化学成分的首次报道，也是苋科中杜松烷类化合物存在的首次报道。
