Perfluorinated chemicals in blood of residents in Wenzhou, China.

Perfluorinated compounds (PFCs) are persistent organic pollutants ubiquitously distributed in the environment and human populations. Here we report PFC concentrations in the residents of Wenzhou City, which is characterized as the 'Footwear Capital' of China. Specifically, fifty serum samples collected from workers in a leather factory, fifty-five umbilical cord serum samples and fifteen serum samples from infertile men were analyzed. PFOS was one of the most frequently detected PFCs and showed the highest level. The mean serum levels of PFOS and PFOA of workers and infertile males were higher than the cord serum. PFOS concentration in cord serum increased with increase in age of the mother. Gender differences were significant both in worker serum samples and umbilical cord samples with higher levels found in males/male fetuses. Our findings suggested that PFOS, PFOA and PFHxS were widely distributed in Wenzhou residents, but occupational exposure was not the main source for workers.