Waikhom Rajesh, Taraphder Abhijit
Department of Nephrology, Institute of Postgraduate Medical and Educational Research, Kolkata, India.
Indian J Dermatol. 2011 Jan;56(1):54-8. doi: 10.4103/0019-5154.77554.
Nephrogenic systemic fibrosis is a fibrosing disorder of the skin that develops in patients with advanced renal failure. It mostly presents with progressive hardening or induration of the skin of the extremities. Systemic involvement is also known to occur in this entity. Exposure to gadolinium contrast for radiological evaluation has been identified as the offending agent. The condition is progressive and can be seriously disabling. Therapeutic options are limited and not rewarding in majority of the cases. Awareness of this entity is important so that proper precautionary measures can be taken at the earliest to ameliorate the condition.
肾源性系统性纤维化是一种发生于晚期肾衰竭患者的皮肤纤维化疾病。它主要表现为四肢皮肤进行性硬化或硬结。已知该疾病也会出现全身受累情况。已确定用于放射学评估的钆对比剂为致病因素。该病呈进行性发展，可导致严重残疾。治疗选择有限，且在大多数病例中效果不佳。认识到这种疾病很重要，以便尽早采取适当的预防措施来改善病情。
