与马奥尼病毒及马奥尼病毒缺失突变体相比，Lsc脊髓灰质炎病毒引发肽链起始对高渗环境的内在抗性更强。
Peptide-chain initiation with Lsc poliovirus is intrinsically more resistant to hypertonic environment than is peptide-chain initiation with Mahoney virus and deletion mutants of Mahoney virus.
作者信息
Tershak D R
出版信息
J Virol. 1978 Dec;28(3):1006-10. doi: 10.1128/JVI.28.3.1006-1010.1978.
Abstract
Peptide-chain initiation with LSc poliovirus was more resistant to hypertonic medium than peptide-chain initiation with Mahoney poliovirus. Protein synthesis of LSc virus retained its relative resistance to high osmolarity created by the addition of excess NaCl to the medium in cells coinfected with Mahoney virus. The data indicate that peptide-chain initiation with LSc virus is intrinsically more resistant to high osmolarity than that of Mahoney virus rather than reflecting different permeability changes in cells after infection. Two Mahoney virus mutants harboring deletions at the 5' end of the viral chromosome exhibited the same sensitivity to excess NaCl as parent virus, suggesting that the original chromosomal region for peptide-chain initiation has not been severely altered by the deletions.
摘要
与马奥尼脊髓灰质炎病毒相比，LSc脊髓灰质炎病毒引发的肽链起始对高渗培养基更具抗性。在与马奥尼病毒共感染的细胞中，向培养基中添加过量氯化钠所产生的高渗透压下，LSc病毒的蛋白质合成仍保持其相对抗性。数据表明，与马奥尼病毒相比，LSc病毒引发的肽链起始本质上对高渗透压更具抗性，而非反映感染后细胞中不同的通透性变化。两个在病毒染色体5'端带有缺失的马奥尼病毒突变体，对过量氯化钠的敏感性与亲本病毒相同，这表明肽链起始的原始染色体区域并未因缺失而发生严重改变。
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1
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Virology. 1955 Dec;1(5):533-5. doi: 10.1016/0042-6822(55)90041-6.
2
Defective interfering particles from poliovirus vaccine and vaccine reference strains.
Virology. 1974 Aug;60(2):579-83. doi: 10.1016/0042-6822(74)90352-3.
3
Selective and reversible inhibition of initiation of protein synthesis in mammalian cells.哺乳动物细胞中蛋白质合成起始的选择性和可逆性抑制。
J Mol Biol. 1974 May 15;85(2):195-211. doi: 10.1016/0022-2836(74)90360-x.
4
Defective interfering particles of poliovirus. II. Nature of the defect.脊髓灰质炎病毒的缺陷干扰颗粒。II. 缺陷的本质。
J Mol Biol. 1973 May 25;76(3):325-43. doi: 10.1016/0022-2836(73)90508-1.
5
Effect of pactamycin on synthesis of poliovirus proteins: a method for genetic mapping.密旋霉素对脊髓灰质炎病毒蛋白合成的影响：一种基因定位方法。
J Virol. 1971 Oct;8(4):395-401. doi: 10.1128/JVI.8.4.395-401.1971.
6
Determination of the gene sequence of poliovirus with pactamycin.用 pactamycin 测定脊髓灰质炎病毒的基因序列。
Proc Natl Acad Sci U S A. 1971 Nov;68(11):2852-6. doi: 10.1073/pnas.68.11.2852.
7
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8
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9
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10
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