Department of Clinical Science, Intervention and Technology, Division of Paediatrics, Endocrine Research Unit B62, Karolinska Institutet, S-141 86 Stockholm, Sweden.
BMC Public Health. 2011 May 18;11:336. doi: 10.1186/1471-2458-11-336.
Overweight and obesity have a dramatic negative impact on children's health not only during the childhood but also throughout the adult life. Preventing the development of obesity in children is therefore a world-wide health priority. There is an obvious urge for sustainable and evidenced-based interventions that are suitable for families with young children, especially for families with overweight or obese parents. We have developed a prevention program, Early STOPP, combating multiple obesity-promoting behaviors such unbalanced diet, physical inactivity and disturbed sleeping patterns. We also aim to evaluate the effectiveness of the early childhood obesity prevention in a well-characterized population of overweight or obese parents. This protocol outlines methods for the recruitment phase of the study.
This randomized controlled trial (RCT) targets overweight and/or obese parents with infants, recruited from the Child Health Care Centers (CHCC) within the Stockholm area. The intervention starts when infants are one year of age and continues until they are six and is regularly delivered by a trained coach (dietitian, physiotherapist or a nurse). The key aspects of Early STOPP family intervention are based on Swedish recommendations for CHCC, which include advices on healthy food choices and eating patterns, increasing physical activity/reducing sedentary behavior and regulating sleeping patterns.
The Early STOPP trial design addresses weaknesses of previous research by recruiting from a well-characterized population, defining a feasible, theory-based intervention and assessing multiple measurements to validate and interpret the program effectiveness. The early years hold promise as a time in which obesity prevention may be most effective. To our knowledge, this longitudinal RCT is the first attempt to demonstrate whether an early, long-term, targeted health promotion program focusing on healthy eating, physical activity/reduced sedentary behaviors and normalizing sleeping patterns could be effective. If proven so, Early STOPP may protect children from the development of overweight and obesity.
The protocol for this study is registered with the clinical trials registry clinicaltrials.gov, ID: ES-2010).
超重和肥胖对儿童健康的影响是巨大的，不仅在儿童时期，而且在整个成年期也是如此。因此，预防儿童肥胖是全世界的健康重点。现在迫切需要可持续和基于证据的干预措施，这些措施适合有年幼子女的家庭，尤其是那些超重或肥胖父母的家庭。我们已经开发了一种预防计划，即早期 STOPP，旨在对抗多种促进肥胖的行为，如饮食不均衡、缺乏身体活动和睡眠模式紊乱。我们还旨在评估针对超重或肥胖父母的幼儿肥胖预防计划的有效性。本方案概述了研究招募阶段的方法。
本随机对照试验（RCT）针对超重和/或肥胖的父母及其 1 岁的婴儿进行，招募自斯德哥尔摩地区的儿童保健中心（CHCC）。干预从婴儿 1 岁时开始，持续到 6 岁，并由经过培训的教练（营养师、理疗师或护士）定期提供。早期 STOPP 家庭干预的关键方面基于瑞典对 CHCC 的建议，包括健康饮食选择和饮食模式的建议、增加身体活动/减少久坐行为和调节睡眠模式。
早期 STOPP 试验设计通过从特征明确的人群中招募、定义可行的、基于理论的干预措施以及评估多个测量值来验证和解释计划的有效性，从而解决了之前研究的弱点。早期是预防肥胖最有效的时期。据我们所知，这是一项旨在证明以健康饮食、身体活动/减少久坐行为和正常化睡眠模式为重点的早期、长期、有针对性的健康促进计划是否有效的首次尝试。如果证明有效，早期 STOPP 可能会保护儿童免受超重和肥胖的发展。
本研究方案在临床试验注册处 clinicaltrials.gov 注册，ID：ES-2010）。
