Luo J C, Nelsen K G, Fischbein A
Department of Community Medicine, Mount Sinai School of Medicine, City University of New York, New York 10029.
Br J Ind Med. 1990 Apr;47(4):239-41. doi: 10.1136/oem.47.4.239.
Two police officers developed asthma like illness after a single but prolonged exposure to toluene diisocyanate (TDI) by being in the immediate vicinity of a tank car that had overturned on a highway. One officer experienced upper and lower respiratory tract symptoms with chest tightness about 4.5 hours after initial exposure. Shortness of breath, cough, and wheezing were noted the following day. The other experienced symptoms immediately on exposure, developed shortness of breath 20 minutes later, and presented with wheezing four hours after that. Follow up examinations over seven years showed persistence of respiratory symptoms and continuation of airway hyperreactivity requiring treatment.
两名警察在高速公路上一辆罐车翻车后，因在罐体附近单次长时间接触甲苯二异氰酸酯（TDI）而患上类似哮喘的疾病。一名警察在初次接触约4.5小时后出现上、下呼吸道症状并伴有胸闷。次日出现呼吸急促、咳嗽和喘息。另一名警察在接触后立即出现症状，20分钟后出现呼吸急促，此后4小时出现喘息。七年的随访检查显示呼吸道症状持续存在，气道高反应性持续存在且需要治疗。
