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经尿道绿激光前列腺剜除术——一项可行性研究。

Transurethral GreenLight laser enucleation of the prostate--a feasibility study.

机构信息

Department of Urology, Asklepios Klinik St. Georg, Hamburg, Germany.

出版信息

J Endourol. 2011 Jul;25(7):1199-201. doi: 10.1089/end.2010.0550. Epub 2011 May 25.

Abstract

BACKGROUND AND PURPOSE

GreenLight laser vaporization is established as a minimally invasive procedure to treat patients with benign prostatic hyperplasia. Despite good functional results, it may be difficult to achieve adequate tissue removal for large prostates. In this study, we evaluated whether a transurethral enucleation technique is feasible with the GreenLight laser as a possible way to improve the amount of tissue removed.

PATIENTS AND METHODS

Following the technique described by Gilling for the holmium laser, we carried out transurethral enucleation of prostate adenoma with the 120W HPS GreenLight laser in 21 consecutive patients. Preoperative data were collected prospectively; prostate volume, International Prostate Symptom Score (IPSS), postvoid residual (PVR), prostate-specific antigen level, peak urinary flow rate, operative time, catherization period, length of hospitalization, and perioperative complications were recorded as well as the weight of the enucleated tissue and the applied laser energy. For follow-up, IPSS and PVR were recorded. Data are presented as mean±standard deviation.

RESULTS

Fifty-two percent of the patients had preoperative urinary retention. Preoperative prostate volume was 74.6±21.7 cc; 34.7±21.7 g of tissue were enucleated. IPSS was reduced from 25±6 to 5±9 (P=0.0001), PVR from 126±80 to 11±18 (P=0.002) by GreenLight laser enucleation. Serious complications were not observed. Operative time was 112±27 minutes. Catheter time was 1.2±0.4 days. The length of hospitalization was 3.6±0.9 days.

CONCLUSION

GreenLight laser enucleation is feasible and safe. Tissue reduction is complete, and good functional results are achieved. All patients were able to void properly. Major complications were not observed. The procedure is technically demanding, resulting in long operative times at the first interventions.

摘要

背景与目的

绿光激光汽化术已被确立为治疗良性前列腺增生的微创方法。尽管功能效果良好,但对于大前列腺,可能难以实现足够的组织切除。在这项研究中,我们评估了经尿道前列腺切除术是否可行,绿光激光作为一种可能的方法来提高切除的组织量。

患者与方法

我们按照 Gilling 为钬激光描述的技术,在 21 例连续患者中使用 120W HPS 绿光激光进行经尿道前列腺切除术。前瞻性收集术前数据;前列腺体积、国际前列腺症状评分(IPSS)、残余尿量(PVR)、前列腺特异性抗原水平、最大尿流率、手术时间、导尿时间、住院时间和围手术期并发症,以及切除的组织重量和应用的激光能量。随访时记录 IPSS 和 PVR。数据以平均值±标准差表示。

结果

52%的患者术前有尿潴留。术前前列腺体积为 74.6±21.7cc;切除的组织为 34.7±21.7g。IPSS 从 25±6 降低到 5±9(P=0.0001),PVR 从 126±80 降低到 11±18(P=0.002)。没有观察到严重的并发症。手术时间为 112±27 分钟。导尿管时间为 1.2±0.4 天。住院时间为 3.6±0.9 天。

结论

绿光激光切除术是可行且安全的。组织减少完全,功能效果良好。所有患者均能正常排尿。未观察到主要并发症。该手术技术要求高,首次干预的手术时间较长。

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