Veloso-Guedes C A, Rosalen S T, Thobias C M, Andreotti R M, Galhardo F D M, Oliveira da Silva A M, Araujo O, Boin I F S F
Surgery Department, State University of Campinas, Campinas, Brazil.
Transplant Proc. 2011 May;43(4):1322-4. doi: 10.1016/j.transproceed.2011.03.057.
Guidelines established by the American Thoracic Society recommend the use of corridors 30 m in length for the 6-minute walk test (6MWT). However, not all institutions have such long corridors, which hinders or prevents 6MWT performance and use of its benefits.
To compare the distances walked by male patients with cirrhosis on the liver transplantation waiting list, we performed 6MWT on corridors 20 and 30 m long.
This prospective study included 10 patients on the waiting list for liver transplantation. They underwent 2 walk tests: the first test in a 20 m corridor and the second in a 30 m corridor. We assessed physiologic variables (heart rate, oxygen saturation, arterial blood pressure) and the subjective sensation of dyspnea at rest at 6 and 9 minutes after each walk. Statistical analysis was performed using the Wilcoxon test.
Data are expressed as mean ± sd. Patient age was 59 ± 10 years. The distances walked by the patients were shorter than those predicted for their age and gender (586 ± 45 m) in both tests, no significant difference was observed between the first and the second 6MWT (437 ± 101 m vs 465 ± 80 m; P=.131) or among the physiologic variables.
We concluded that a 20 m corridor can be used safely and effectively as an alternative to 30 m for the 6MWT for male patients with cirrhosis on the liver transplantation waiting list.
美国胸科学会制定的指南建议在6分钟步行试验（6MWT）中使用长度为30米的走廊。然而，并非所有机构都有如此长的走廊，这阻碍或无法进行6MWT及其益处的应用。
为了比较肝移植等待名单上男性肝硬化患者的步行距离，我们在20米和30米长的走廊上进行了6MWT。
这项前瞻性研究纳入了10名肝移植等待名单上的患者。他们进行了2次步行试验：第一次试验在20米长的走廊进行，第二次试验在30米长的走廊进行。我们评估了每次步行后6分钟和9分钟时的生理变量（心率、血氧饱和度、动脉血压）以及静息时的主观呼吸困难感觉。使用Wilcoxon检验进行统计分析。
数据以均值±标准差表示。患者年龄为59±10岁。在两次试验中，患者的步行距离均短于根据其年龄和性别预测的距离（586±45米），第一次和第二次6MWT之间（437±101米对465±80米；P = 0.131）或生理变量之间均未观察到显著差异。
我们得出结论，对于肝移植等待名单上的男性肝硬化患者，20米长的走廊可安全有效地替代30米长的走廊用于6MWT。
