Department of Chemistry, Faculty of Sciences, Atatürk University, Erzurum, Turkey.
Int J Food Sci Nutr. 2011 Dec;62(8):821-5. doi: 10.3109/09637486.2011.585963. Epub 2011 Jun 2.
Caffeic acid phenethyl ester (CAPE), a plant polyphenolic concentrated in honeybee propolis, has been found to be biologically active in a variety of pathways. The aim of this study was to determine the antioxidant activity of CAPE using different methods such as total antioxidant activity by the thiocyanate method, 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid radicals, 1,1-diphenyl-2-picryl-hydrazyl free radicals, N,N-dimethyl-p-phenylenediamine dihydrochloride radicals and superoxide anion radicals scavenging activities, reducing power and ferrous ions (Fe(2+)) chelating activities. CAPE showed 97.9% inhibition on lipid peroxidation of linoleic acid emulsion. On the other hand, butylated hydroxyanisole, butylated hydroxytoluene, α-tocopherol and trolox indicated an inhibition of 87.3, 97.6, 75.3 and 90.3% on peroxidation in the same system, respectively.
咖啡酸苯乙酯（CAPE）是一种存在于蜂胶中的植物多酚，已被发现具有多种生物活性途径。本研究旨在使用不同的方法来确定 CAPE 的抗氧化活性，如硫氰酸盐法测定总抗氧化活性、2,2'-联氮-双（3-乙基苯并噻唑啉-6-磺酸）自由基、1,1-二苯基-2-苦基肼自由基、N,N-二甲基-对苯二胺二盐酸盐自由基和超氧阴离子自由基清除活性、还原力和亚铁离子（Fe(2+)）螯合活性。CAPE 对亚油酸乳液的脂质过氧化抑制率达到 97.9%。另一方面，丁基羟基茴香醚、丁基羟基甲苯、α-生育酚和 Trolox 在相同体系中的抑制率分别为 87.3%、97.6%、75.3%和 90.3%。
