Ueno T, Saijo K
Dept. of Ophthalmol., Sapporo Medical College, Japan.
Nippon Ganka Gakkai Zasshi. 1990 Jan;94(1):44-8.
A commercial alcoholic disinfectant (Welpas) was tested for its activity against adenovirus type 3 (Ad 3) by using two procedures, the in vitro suspension test and the in vivo fingertip test. Other available techniques for the sterilization of fingers were also evaluated for removal of Ad by using the fingertip test. In the suspension tests, the infectivity of Ad 3 was reduced to undetectable levels within 30-60 seconds. This results suggest the effectiveness of this disinfectant in reducing Ad infectivity. In the fingertip tests, the viruses were recovered from fingertips in varying titers after using one of the following techniques: wiping with tissue papers, washing with running water, washing with soap and rinsing with water, rubbing with Welpas, wiping with cotton soaked in 70% alcohol, or washing with a brush under running water. However, the viruses were not recovered when the fingertip was washed with water, wiped with paper, and rubbed with Welpas successively. This technique was found to be the most effective method currently available.
通过体外悬浮试验和体内指尖试验这两种方法，对一种商用酒精消毒剂（Welpas）针对3型腺病毒（Ad 3）的活性进行了测试。还使用指尖试验评估了其他现有的手指消毒技术对腺病毒的去除效果。在悬浮试验中，Ad 3的传染性在30至60秒内降至无法检测的水平。这些结果表明这种消毒剂在降低腺病毒传染性方面是有效的。在指尖试验中，使用以下技术之一后，从指尖回收的病毒滴度各不相同：用纸巾擦拭、用流水冲洗、用肥皂洗手并用水冲洗、用Welpas擦拭、用浸泡在70%酒精中的棉花擦拭或在流水下用刷子刷洗。然而，当指尖依次用水冲洗、用纸擦拭并用Welpas擦拭后，未回收病毒。该技术被发现是目前最有效的方法。
