• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

疣状表皮发育不良相关人乳头瘤病毒呈现出调控基因组区域的亚属特异性组织形式。

Epidermodysplasia verruciformis associated human papillomaviruses present a subgenus-specific organization of the regulatory genome region.

作者信息

Ensser A, Pfister H

机构信息

Institut für Klinische und Molekulare Virologie, Universität Erlangen-Nürnberg, FRG.

出版信息

Nucleic Acids Res. 1990 Jul 11;18(13):3919-22. doi: 10.1093/nar/18.13.3919.

DOI:10.1093/nar/18.13.3919
PMID:2165253
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC331094/
Abstract

The regulatory regions of the human papillomaviruses (HPVs) 9, 17, 20, and 36 were mapped, sequenced, and aligned. They revealed an arrangement of putative protein binding sites specific for the epidermodysplasia verruciformis associated HPVs. Three subgroups could be differentiated.

摘要

对人乳头瘤病毒9型、17型、20型和36型的调控区域进行了定位、测序和比对。结果显示了与疣状表皮发育不良相关的人乳头瘤病毒特有的假定蛋白质结合位点排列方式。可区分出三个亚组。

相似文献

1
Epidermodysplasia verruciformis associated human papillomaviruses present a subgenus-specific organization of the regulatory genome region.疣状表皮发育不良相关人乳头瘤病毒呈现出调控基因组区域的亚属特异性组织形式。
Nucleic Acids Res. 1990 Jul 11;18(13):3919-22. doi: 10.1093/nar/18.13.3919.
2
Genetic relationship among human papillomaviruses associated with benign and malignant tumours of patients with epidermodysplasia verruciformis.疣状表皮发育不良患者良性和恶性肿瘤相关人乳头瘤病毒之间的遗传关系。
J Gen Virol. 1987 Dec;68 ( Pt 12):3091-103. doi: 10.1099/0022-1317-68-12-3091.
3
Differences in transforming activity and coded amino acid sequence among E6 genes of several papillomaviruses associated with epidermodysplasia verruciformis.与疣状表皮发育不良相关的几种乳头瘤病毒的E6基因在转化活性和编码氨基酸序列上的差异。
Virology. 1992 Feb;186(2):628-39. doi: 10.1016/0042-6822(92)90029-o.
4
Human papillomavirus type 38 isolated from patients with epidermodysplasia verruciformis.
Intervirology. 1986;26(1-2):104-8. doi: 10.1159/000149687.
5
Human papillomavirus (HPV) type 50, a type associated with epidermodysplasia verruciformis (EV) and only weakly related to other EV-specific HPVs.人乳头瘤病毒50型，一种与疣状表皮发育异常症（EV）相关的类型，与其他特定于EV的人乳头瘤病毒仅有微弱关联。
J Virol. 1989 Nov;63(11):4910. doi: 10.1128/JVI.63.11.4910-.1989.
6
High prevalence of a variety of epidermodysplasia verruciformis-associated human papillomaviruses in psoriatic skin of patients treated or not treated with PUVA.接受或未接受补骨脂素加紫外线A（PUVA）治疗的银屑病患者皮肤中多种疣状表皮发育不良相关人乳头瘤病毒的高流行率
J Invest Dermatol. 1999 Jul;113(1):122-6. doi: 10.1046/j.1523-1747.1999.00641.x.
7
Unique topography of DNA-protein interactions in the non-coding region of epidermodysplasia verruciformis-associated human papillomaviruses.疣状表皮发育不良相关人乳头瘤病毒非编码区DNA-蛋白质相互作用的独特拓扑结构
J Gen Virol. 1991 Dec;72 ( Pt 12):2989-97. doi: 10.1099/0022-1317-72-12-2989.
8
Two human papillomavirus DNAs molecularly cloned from a patient with epidermodysplasia verruciformis: restriction maps.
Acta Med Okayama. 1988 Aug;42(4):243-5. doi: 10.18926/AMO/30999.
9
Genetic heterogeneity among human papillomaviruses (HPV) associated with epidermodysplasia verruciformis: evidence for multiple allelic forms of HPV5 and HPV8 E6 genes.与疣状表皮发育不良相关的人乳头瘤病毒（HPV）的遗传异质性：HPV5和HPV8 E6基因存在多种等位基因形式的证据。
Virology. 1991 Oct;184(2):492-503. doi: 10.1016/0042-6822(91)90419-c.
10
Genome organization and taxonomic position of human papillomavirus type 47 inferred from its DNA sequence.根据人乳头瘤病毒47型的DNA序列推断其基因组结构和分类地位。
Virology. 1990 Jul;177(1):401-5. doi: 10.1016/0042-6822(90)90500-q.

引用本文的文献

1
Isolation of three novel rat and mouse papillomaviruses and their genomic characterization.分离三种新型大鼠和小鼠乳头瘤病毒及其基因组特征。
PLoS One. 2012;7(10):e47164. doi: 10.1371/journal.pone.0047164. Epub 2012 Oct 15.
2
Evolutionary variation of papillomavirus E2 protein and E2 binding sites.乳头瘤病毒 E2 蛋白和 E2 结合位点的进化变异。
Virol J. 2011 Aug 1;8:379. doi: 10.1186/1743-422X-8-379.
3
Characterization of novel cutaneous human papillomavirus genotypes HPV-150 and HPV-151.鉴定新型皮肤人乳头瘤病毒 HPV-150 和 HPV-151 基因型。
PLoS One. 2011;6(7):e22529. doi: 10.1371/journal.pone.0022529. Epub 2011 Jul 25.
4
Comprehensive comparison of the interaction of the E2 master regulator with its cognate target DNA sites in 73 human papillomavirus types by sequence statistics.通过序列统计对73种人乳头瘤病毒类型中E2主调节因子与其同源靶DNA位点的相互作用进行全面比较。
Nucleic Acids Res. 2008 Feb;36(3):756-69. doi: 10.1093/nar/gkm1104. Epub 2007 Dec 15.
5
UV-B irradiation stimulates the promoter activity of the high-risk, cutaneous human papillomavirus 5 and 8 in primary keratinocytes.紫外线B照射可刺激原代角质形成细胞中高危皮肤人乳头瘤病毒5型和8型的启动子活性。
Arch Virol. 2005 Jan;150(1):145-51. doi: 10.1007/s00705-004-0398-4. Epub 2004 Oct 5.
6
E2 represses the late gene promoter of human papillomavirus type 8 at high concentrations by interfering with cellular factors.E2在高浓度时通过干扰细胞因子来抑制人乳头瘤病毒8型的晚期基因启动子。
J Virol. 1996 Jan;70(1):119-26. doi: 10.1128/JVI.70.1.119-126.1996.
7
Genetic heterogeneity of oncogenic human papillomavirus type 5 (HPV5) and phylogeny of HPV5 variants associated with epidermodysplasia verruciformis.致癌性人乳头瘤病毒5型（HPV5）的遗传异质性以及与疣状表皮发育不良相关的HPV5变体的系统发育
J Clin Microbiol. 1993 Nov;31(11):2918-26. doi: 10.1128/jcm.31.11.2918-2926.1993.
8
Low-affinity E2-binding site mediates downmodulation of E2 transactivation of the human papillomavirus type 8 late promoter.低亲和力E2结合位点介导人乳头瘤病毒8型晚期启动子E2反式激活的下调。
J Virol. 1994 Nov;68(11):6959-66. doi: 10.1128/JVI.68.11.6959-6966.1994.
9
Nested PCR approach for detection and typing of epidermodysplasia verruciformis-associated human papillomavirus types in cutaneous cancers from renal transplant recipients.巢式聚合酶链反应方法用于检测和分型肾移植受者皮肤癌中与疣状表皮发育不良相关的人乳头瘤病毒类型
J Clin Microbiol. 1995 Mar;33(3):690-5. doi: 10.1128/jcm.33.3.690-695.1995.
10
Analysis of genomic sequences of 95 papillomavirus types: uniting typing, phylogeny, and taxonomy.95种乳头瘤病毒基因组序列分析：统一分型、系统发育和分类学
J Virol. 1995 May;69(5):3074-83. doi: 10.1128/JVI.69.5.3074-3083.1995.

本文引用的文献

1
A comprehensive set of sequence analysis programs for the VAX.一套适用于VAX的综合序列分析程序。
Nucleic Acids Res. 1984 Jan 11;12(1 Pt 1):387-95. doi: 10.1093/nar/12.1part1.387.
2
Biochemical characterization of two types of human papillomaviruses associated with epidermodysplasia verruciformis.与疣状表皮发育不良相关的两种人类乳头瘤病毒的生化特征
J Virol. 1982 Aug;43(2):436-47. doi: 10.1128/JVI.43.2.436-447.1982.
3
Molecular cloning and characterization of the DNAs of human papillomaviruses 19, 20, and 25 from a patient with epidermodysplasia verruciformis.从一名疣状表皮发育不良患者中克隆和鉴定人乳头瘤病毒19、20和25的DNA
J Virol. 1984 Dec;52(3):1019-23. doi: 10.1128/JVI.52.3.1019-1023.1984.
4
Molecular cloning and characterization of the genomes of nine newly recognized human papillomavirus types associated with epidermodysplasia verruciformis.与疣状表皮发育不良相关的9种新确认的人乳头瘤病毒基因组的分子克隆与特性分析
J Virol. 1984 Dec;52(3):1013-8. doi: 10.1128/JVI.52.3.1013-1018.1984.
5
Naturally occurring poly(dA-dT) sequences are upstream promoter elements for constitutive transcription in yeast.天然存在的聚（dA-dT）序列是酵母中组成型转录的上游启动子元件。
Proc Natl Acad Sci U S A. 1985 Dec;82(24):8419-23. doi: 10.1073/pnas.82.24.8419.
6
Trans-acting protein factors and the regulation of eukaryotic transcription: lessons from studies on DNA tumor viruses.反式作用蛋白因子与真核转录调控：来自DNA肿瘤病毒研究的经验教训
Genes Dev. 1988 Mar;2(3):267-81. doi: 10.1101/gad.2.3.267.
7
Viral myb oncogene encodes a sequence-specific DNA-binding activity.病毒原癌基因myb编码一种序列特异性DNA结合活性。
Nature. 1988 Oct 27;335(6193):835-7. doi: 10.1038/335835a0.
8
Nucleotide sequence and genome organization of human papillomavirus type 5.人乳头瘤病毒5型的核苷酸序列与基因组结构
Virology. 1987 May;158(1):251-4. doi: 10.1016/0042-6822(87)90263-7.
9
Characterization of a new type of human papillomavirus (HPV) related to HPV5 from a case of actinic keratosis.从一例光化性角化病病例中鉴定出一种与HPV5相关的新型人乳头瘤病毒（HPV）。
Virology. 1986 Oct 30;154(2):389-94. doi: 10.1016/0042-6822(86)90464-2.
10
Epidermodysplasia verruciformis-associated human papillomavirus 8: genomic sequence and comparative analysis.疣状表皮发育不良相关人乳头瘤病毒8型：基因组序列及比较分析
J Virol. 1986 May;58(2):626-34. doi: 10.1128/JVI.58.2.626-634.1986.