内源性小鼠乳腺肿瘤病毒在五个重组近交系组中的分离模式。
Segregation patterns of endogenous mouse mammary tumor viruses in five recombinant inbred strain sets.
作者信息
Lee B K, Eicher E M
机构信息
Jackson Laboratory, Bar Harbor, Maine 04609.
出版信息
J Virol. 1990 Sep;64(9):4568-72. doi: 10.1128/JVI.64.9.4568-4572.1990.
We identified mouse mammary tumor proviral loci in the AKR/J, C3H/HeJ, C57BL/6J, C57L/J, DBA/2J, and SWR/J inbred mouse strains and determined their segregation patterns in the AKXD, AKXL, BXD, BXH, and SWXL recombinant inbred strain sets. Two new Mtv loci, Mtv-29 and Mtv-30, were identified. Mtv-30 was genetically mapped to chromosome 12. Additionally, two previously identified Mtv loci, Mtv-14 and Mtv-23, were genetically mapped to chromosome 4 and chromosome 6, respectively.
我们在AKR/J、C3H/HeJ、C57BL/6J、C57L/J、DBA/2J和SWR/J近交系小鼠品系中鉴定出小鼠乳腺肿瘤前病毒基因座，并确定了它们在AKXD、AKXL、BXD、BXH和SWXL重组近交系组中的分离模式。鉴定出两个新的Mtv基因座，即Mtv-29和Mtv-30。Mtv-30被基因定位到12号染色体。此外，两个先前鉴定的Mtv基因座，Mtv-14和Mtv-23，分别被基因定位到4号染色体和6号染色体。
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