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化学刺激沉香、野生沉香和健康白木香(Aquilaria sinensis (Lour.) gilg)精油的成分比较及抗菌活性研究。

Comparison of compositions and antimicrobial activities of essential oils from chemically stimulated agarwood, wild agarwood and healthy Aquilaria sinensis (Lour.) gilg trees.

机构信息

Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, 100193 Beijing, China.

出版信息

Molecules. 2011 Jun 14;16(6):4884-96. doi: 10.3390/molecules16064884.

Abstract

The composition and antimicrobial activity of the essential oils which were obtained from agarwood originated from Aquilaria sinensis (Lour.) Gilg stimulated by the chemical method (S1) were characterized, taking wild agarwood (S2) and healthy trees (S3) respectively as the positive and negative controls. The chemical composition of S1 was investigated by gas chromatography-mass spectrometry (GC-MS). The essential oil of S1 showed a similar composition to that of S2, being rich in sesquiterpenes and aromatic constituents. However, the essential oil of S3 was abundant in fatty acids and alkanes. Essential oils of S1 and S2 had better inhibition activities towards Bacillus subtilis and Staphyloccus aureus, compared with essential oil of S3. Escherichia coli was not sensitive to any of them.

摘要

采用化学刺激法(S1)从瑞香科沉香属白木香(Aquilaria sinensis(Lour.)Gilg)中提取的精油的组成和抗菌活性进行了表征,以野生白木香(S2)和健康树木(S3)分别作为阳性和阴性对照。采用气相色谱-质谱联用(GC-MS)法对 S1 的化学成分进行了分析。S1 的精油组成与 S2 相似,富含倍半萜和芳香族成分。然而,S3 的精油富含脂肪酸和烷烃。与 S3 相比,S1 和 S2 的精油对枯草芽孢杆菌和金黄色葡萄球菌有更好的抑制活性。大肠杆菌对它们均不敏感。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fa9/6264414/bc5c8b9b9d4a/molecules-16-04884-g001.jpg

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