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GC-MS 研究不同亚洲国家的 (Lour.)Gilgorgans 和沉香的化学成分。

GC-MS Study of the Chemical Components of Different (Lour.) Gilgorgans and Agarwood from Different Asian Countries.

机构信息

Key Laboratory of Bio-Based Material Science and Technology (Ministry of Education), College of Material Science and Engineering, Northeast Forestry University, Harbin 150040, China.

Key Laboratory of Pulp and Paper Science & Technology of Ministry of Education/Shandong Province, Qilu University of Technology, Jinan 250353, China.

出版信息

Molecules. 2018 Aug 28;23(9):2168. doi: 10.3390/molecules23092168.

Abstract

As a traditional medicinal herb and valuable natural spice in China, (Lour.) Gilg has many significant pharmacological effects. Agarwood is the resinous heartwood acquired from wounded trees, and is widely used in pharmaceuticals owing to its excellent medicinal value. In this study, the chemical composition of volatile components and alcohol extracts from different organs of and agarwoods grown in different regions were investigated using GC-MS. The results showed that Vietnam agarwood had the highest moisture content, which was attributed to the local climate, while the fruit and bark of had higher moisture contents than the other organs. The volatile components of organs included 3-ethyl-5-(2-ethylbutyl)-octadecane, oleic acid 3-(octadecyloxy) propyl ester, and docosanoic acid 1,2,3-propanetriyl ester, while the alcohol extracts of organs contained benzoic acid ethyl ester, hexadecanoic acid ethyl ester, oleic acid, and -hexadecanoic acid. Furthermore, the main active ingredients in agarwood from different habitats were sesquiterpenoids, aromatic species, and chromone compounds. The role of chromone compound 2-phenylethyl-benzopyran as an elicitor and the mechanism of agarwood formation were also investigated. Antioxidant tests showed that essential oils from agarwood and had antioxidant capacities by comparison with butylated hydroxytoluene and vitamin E. An antibacterial activity test showed that the inhibition effect of the essential oil was better against Gram-positive bacteria than against Gram-negative bacteria.

摘要

作为中国传统药用植物和有价值的天然香料,(Lour.)吉尔格具有许多重要的药理作用。沉香是从受伤的树木中获得的树脂状心材,由于其优异的药用价值,被广泛应用于制药行业。在这项研究中,使用 GC-MS 研究了不同地区生长的和沉香不同器官的挥发油成分和醇提物的化学成分。结果表明,越南沉香的水分含量最高,这归因于当地的气候,而沉香的果实和树皮的水分含量高于其他器官。沉香器官的挥发性成分包括 3-乙基-5-(2-乙基丁基)-十八烷、油酸 3-(十八烷基氧基)丙酯和二十二烷酸 1,2,3-丙三醇酯,而沉香器官的醇提物含有苯甲酸乙酯、十六烷酸乙酯、油酸和 -十六烷酸。此外,不同生境沉香的主要活性成分是倍半萜、芳香族和色酮类化合物。还研究了色酮化合物 2-苯乙基-苯并吡喃作为诱导剂的作用以及沉香形成的机制。抗氧化试验表明,与丁基羟基甲苯和维生素 E 相比,沉香和的精油具有抗氧化能力。抗菌活性试验表明,精油对革兰氏阳性菌的抑制效果优于革兰氏阴性菌。

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