Lakhal K, Faidherbe J, Choukhi R, Boissier E, Capdevila X
Réanimation polyvalente, service d'anesthésie-réanimation A, hôpital Lapeyronie, centre hospitalier universitaire, 375, avenue du Doyen-Gaston-Giraud, 34295 Montpellier cedex 5, France.
Ann Fr Anesth Reanim. 2011 Jul-Aug;30(7-8):e1-3. doi: 10.1016/j.annfar.2011.04.002. Epub 2011 Jun 15.
Povidone iodine (PI), a skin antiseptic, is sometimes used internally but this procedure exposes to potentially lethal iodine absorption. Indeed, a 41-year-old woman, with no relevant medical history, developed a transient hypotension, anuric renal failure, hemolysis, coagulopathy and uterine infarction after intra-uterine injection of PI as a dye to check the fallopian tube patency (hydrotubation). Iodemia peaked at 6929 μg/dL (normal range 3.4-8.0 μg/dL), and decreased over the 9 days of renal replacement therapy. Extreme caution should be exercised when PI is in contact with a mucosa, the early recognition of iodine toxicity being of utmost importance to rapidly prompt renal replacement therapy. The main purpose of this report is to highlight the clinical features of PI absorption, whatever the route of administration.
聚维酮碘（PI）是一种皮肤消毒剂，有时也用于体内，但这种做法会导致潜在的致命性碘吸收。实际上，一名41岁无相关病史的女性，在子宫内注射PI作为染料以检查输卵管通畅性（输卵管通液术）后，出现了短暂性低血压、无尿性肾衰竭、溶血、凝血病和子宫梗死。碘血症峰值达到6929μg/dL（正常范围为3.4 - 8.0μg/dL），并在肾脏替代治疗的9天内下降。当PI与黏膜接触时应格外小心，尽早识别碘中毒对于迅速启动肾脏替代治疗至关重要。本报告的主要目的是强调无论给药途径如何，PI吸收的临床特征。
