Martínez-Arán Anabel, Torrent Carla, Solé Brisa, Bonnín C Mar, Rosa Adriane R, Sánchez-Moreno José, Vieta Eduard
Early Onset Psychosis Program & Bipolar Disorders Program, Clinical Institute of Neuroscience, Hospital Clinic of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Spain.
Clin Pract Epidemiol Ment Health. 2011;7:112-6. doi: 10.2174/1745017901107010112. Epub 2011 Jun 6.
Neurocognitive impairment constitutes a core feature of bipolar illness. The main domains affected are verbal memory, attention, and executive functions. Deficits in these areas as well as difficulties to get functional remission seem to be increased associated with illness progression. Several studies have found a strong relationship between neurocognitive impairment and low functioning in bipolar disorder, as previously reported in other illnesses such as schizophrenia. Cognitive remediation strategies, adapted from work conducted with traumatic brain injury patients and applied to patients with schizophrenia, also need to be adapted to individuals with bipolar disorders. Early intervention using functional remediation, involves neurocognitive techniques and training, but also psychoeducation on cognition-related issues and problem-solving within an ecological framework.
神经认知障碍是双相情感障碍的核心特征。受影响的主要领域是言语记忆、注意力和执行功能。随着疾病进展，这些领域的缺陷以及实现功能缓解的困难似乎会增加。几项研究发现，神经认知障碍与双相情感障碍患者的低功能之间存在密切关系，正如先前在精神分裂症等其他疾病中所报道的那样。从针对创伤性脑损伤患者开展的工作中改编而来并应用于精神分裂症患者的认知康复策略，也需要适用于双相情感障碍患者。使用功能康复的早期干预，涉及神经认知技术和训练，还包括在生态框架内就认知相关问题和解决问题进行心理教育。
