Kakimi K, Kishida Y, Higuchi I, Kiyomasu T, Sakai H, Shibata R, Yanagawa S, Adachi A, Ishimoto A
Department of Viral Oncology, Kyoto University.
Jpn J Cancer Res. 1990 Aug;81(8):768-72. doi: 10.1111/j.1349-7006.1990.tb02643.x.
Endogenous feline leukemia RD114 virus genome rendered capable of infecting mouse cells by phenotypic mixing with an ecotropic murine leukemia virus (MuLV) exhibited the Fv-1 restriction pattern of the ecotropic murine virus. However, RD114 genomes phenotypically mixed with ecotropic MuLV showed one-hit dose-response kinetics, even when titrated with murine cells with the restricted Fv-1 phenotype.
通过与嗜亲性鼠白血病病毒（MuLV）进行表型混合而具备感染小鼠细胞能力的内源性猫白血病RD114病毒基因组，呈现出嗜亲性鼠病毒的Fv-1限制模式。然而，即使在用具有受限Fv-1表型的鼠细胞进行滴定的情况下，与嗜亲性MuLV进行表型混合的RD114基因组也表现出单打击剂量反应动力学。
