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家庭眼压测量在小儿青光眼治疗中的应用。

Home tonometry for management of pediatric glaucoma.

机构信息

Duke Eye Center, Durham, North Carolina.

Duke Eye Center, Durham, North Carolina.

出版信息

Am J Ophthalmol. 2011 Sep;152(3):470-478.e2. doi: 10.1016/j.ajo.2011.03.001.

Abstract

PURPOSE

To use iCare rebound tonometry in the home setting for documentation of diurnal intraocular pressure (IOP) fluctuations in children.

DESIGN

Nonrandomized, prospective clinical study.

METHODS

Pediatric ophthalmology clinic patients were recruited between October 2009 and February 2010 who were able to cooperate with IOP measurement by iCare rebound tonometry and whose caregiver was willing and able to obtain iCare measurements at home. The child's IOP was measured first by iCare tonometry followed by a second method (Goldmann applanation [GAT]). The caregiver was instructed on the use of the iCare tonometer. The subject's IOP was measured by the caregiver at home at designated time periods for at least 2 consecutive days.

RESULTS

Seventeen children (17 eyes) with known or suspected glaucoma and 11 normal children were included. Excellent reliability was obtained by caregivers in 70% of iCare measurements. Mean difference between iCare and GAT in clinic was 2.0 ± 4.0 mm Hg, P = .08. Daily IOP fluctuation occurred in both subjects with glaucoma and normal subjects. In children with known or suspected glaucoma, relative peak and trough IOPs occurred in the early morning (45%) and late evening (43.5%), respectively. Comparison of the peak IOP measured at home vs in the clinic was >6 mm Hg in 5 of 16 subjects (31%) and affected glaucoma management in several subjects.

CONCLUSIONS

In selected children with glaucoma, home tonometry by iCare rebound tonometry was reliable, easily performed by caregivers, and well tolerated, and offered IOP information valuable in clinical management.

摘要

目的

在家中使用 iCare 回弹眼压计记录儿童日间眼压(IOP)波动情况。

设计

非随机、前瞻性临床研究。

方法

2009 年 10 月至 2010 年 2 月期间,我们招募了能够通过 iCare 回弹眼压计配合眼压测量且其照顾者愿意并能够在家中获得 iCare 测量值的儿科眼科诊所患者。首先使用 iCare 眼压计测量儿童的 IOP,然后使用第二种方法(压平眼压计 [GAT])进行测量。照顾者接受了 iCare 眼压计使用方法的指导。照顾者在家中按照指定的时间间隔至少连续两天为儿童测量 IOP。

结果

共纳入 17 名(17 只眼)患有已知或疑似青光眼的儿童和 11 名正常儿童。照顾者在 70%的 iCare 测量中获得了极好的可靠性。诊所内 iCare 和 GAT 之间的平均差异为 2.0±4.0mmHg,P=0.08。青光眼和正常儿童均出现日间 IOP 波动。在已知或疑似青光眼的儿童中,相对峰谷眼压分别出现在清晨(45%)和傍晚(43.5%)。在家中测量的峰值眼压与诊所测量值相比,有 5 名(31%)受试者超过 6mmHg,这对几名受试者的青光眼管理产生了影响。

结论

在家中使用 iCare 回弹眼压计为部分青光眼儿童进行眼压测量是可靠的,照顾者易于操作,且儿童可耐受,提供了有临床管理价值的眼压信息。

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