前处理延迟降低了 QuantiFERON-TB gold in-tube 检测法检测潜伏性结核感染的敏感性。
Preanalytical delay reduces sensitivity of QuantiFERON-TB gold in-tube assay for detection of latent tuberculosis infection.
机构信息
3375 Hillview Avenue, Room 1602, Palo Alto, CA 94304, USA.
出版信息
J Clin Microbiol. 2011 Aug;49(8):3061-4. doi: 10.1128/JCM.01136-11. Epub 2011 Jun 22.
Abstract
The effects of incubation delays on the accuracy of the QuantiFERON-TB gold in-tube assay (QFT-GIT) were measured. Compared to immediate incubation, 6- and 12-hour delays resulted in positive-to-negative reversion rates of 19% (5/26) and 22% (5/23), respectively. These findings underscore the need for standardizing QFT-GIT preanalytical practices.
摘要
检测孵育延迟对 QuantiFERON-TB gold in-tube assay（QFT-GIT）准确性的影响。与即时孵育相比，6 小时和 12 小时延迟导致结果由阳性转为阴性的比例分别为 19%（26 例中的 5 例）和 22%（23 例中的 5 例）。这些发现强调了标准化 QFT-GIT 分析前操作的必要性。
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