Teixeira Juliana Araujo, Baggio Maria Luiza, Giuliano Anna R, Fisberg Regina Mara, Marchioni Dirce Maria Lobo
Nutrition and Public Health Program, Nutrition Department, School of Public Health, University of São Paulo, São Paulo-SP, Brazil.
J Am Diet Assoc. 2011 Jul;111(7):1045-51. doi: 10.1016/j.jada.2011.04.006.
The Natural History of Human Papillomavirus (HPV) Infection in Men: The HIM Study is a prospective multicenter cohort study that, among other factors, analyzes participants' diet. A parallel cross-sectional study was designed to evaluate the validity and reproducibility of the quantitative food frequency questionnaire (QFFQ) used in the Brazilian center from the HIM Study. For this, a convenience subsample of 98 men aged 18 to 70 years from the HIM Study in Brazil answered three 54-item QFFQ and three 24-hour recall interviews, with 6-month intervals between them (data collection January to September 2007). A Bland-Altman analysis indicated that the difference between instruments was dependent on the magnitude of the intake for energy and most nutrients included in the validity analysis, with the exception of carbohydrates, fiber, polyunsaturated fat, vitamin C, and vitamin E. The correlation between the QFFQ and the 24-hour recall for the deattenuated and energy-adjusted data ranged from 0.05 (total fat) to 0.57 (calcium). For the energy and nutrients consumption included in the validity analysis, 33.5% of participants on average were correctly classified into quartiles, and the average value of 0.26 for weighted kappa shows a reasonable agreement. The intraclass correlation coefficients for all nutrients were greater than 0.40 in the reproducibility analysis. The QFFQ demonstrated good reproducibility and acceptable validity. The results support the use of this instrument in the HIM Study.
男性人乳头瘤病毒（HPV）感染的自然史：HIM研究是一项前瞻性多中心队列研究，除其他因素外，该研究还分析了参与者的饮食情况。一项平行横断面研究旨在评估HIM研究巴西中心所使用的定量食物频率问卷（QFFQ）的有效性和可重复性。为此，从巴西HIM研究中选取了98名年龄在18至70岁之间的男性作为便利子样本，他们回答了三份包含54个条目的QFFQ以及三份24小时回顾访谈，两次调查之间间隔6个月（数据收集时间为2007年1月至9月）。布兰德-奥特曼分析表明，两种测量工具之间的差异取决于能量摄入以及有效性分析中所包含的大多数营养素的摄入量，但碳水化合物、纤维、多不饱和脂肪、维生素C和维生素E除外。去衰减和能量调整后的数据中，QFFQ与24小时回顾之间的相关性范围为0.05（总脂肪）至0.57（钙）。对于有效性分析中所包含的能量和营养素消耗情况，平均有33.5%的参与者被正确分类到四分位数中，加权kappa的平均值为0.26，显示出合理的一致性。在可重复性分析中，所有营养素的组内相关系数均大于0.40。QFFQ显示出良好的可重复性和可接受的有效性。这些结果支持在HIM研究中使用该工具。
