Unit of Neonatology, Hôpital des enfants, Toulouse, France.
Acta Paediatr. 2011 Dec;100(12):1548-54. doi: 10.1111/j.1651-2227.2011.02389.x. Epub 2011 Jul 14.
To determine whether growth, feeding tolerance and infectious events of preterm infants is related to the proportion of intake of mother's own raw milk (maternal milk) versus pooled pasteurized banked breast milk (donor milk).
This is a prospective observational study of 55 premature infants born less than 32 weeks of gestational age admitted to the neonatal intensive care unit at the Children's Hospital of Toulouse during two 6-month periods from 2003 to 2005. Enrolled infants were exclusively on enteral feeds with maternal milk ± donor milk.
Mean gestational age was 28.6 weeks (SD 1.5) and mean birth weight 1105 grams (SD 282). During the time of exclusively breast milk feeds, weight gain (g/kg/day) was correlated to the proportion of maternal milk consumed (p = 0.0048, r = 0.4). Necrotizing enterocolitis was inversely correlated to the amount of maternal milk. The amount of maternal milk did not impact on infectious events.
Mother's own raw milk improves weight gain compared with donor milk in preterm infants. Lactation strategies should be sought that helps mothers to increase their milk production.
确定早产儿的生长、喂养耐受和感染事件是否与摄入母亲的初乳（母乳）与集中巴氏消毒的捐献母乳（捐赠奶）的比例有关。
这是一项对 2003 年至 2005 年期间在图卢兹儿童医院新生儿重症监护病房住院的 55 名胎龄小于 32 周的早产儿进行的前瞻性观察研究。入组婴儿均接受肠内喂养，使用母乳+/-捐赠奶。
平均胎龄为 28.6 周（标准差 1.5），平均出生体重为 1105 克（标准差 282 克）。在纯母乳喂养期间，体重增加（g/kg/天）与母乳摄入量的比例呈正相关（p=0.0048，r=0.4）。坏死性小肠结肠炎与母乳量呈负相关。母乳量对感染事件无影响。
与捐赠奶相比，母亲的初乳可改善早产儿的体重增加。应寻求促进母亲泌乳的哺乳策略。
