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本文引用的文献

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Optimizing endothelial targeting by modulating the antibody density and particle concentration of anti-ICAM coated carriers.通过调节抗 ICAM 涂层载体的抗体密度和粒子浓度来优化内皮靶向性。
J Control Release. 2011 Feb 28;150(1):37-44. doi: 10.1016/j.jconrel.2010.10.025. Epub 2010 Nov 1.
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Computational model for nanocarrier binding to endothelium validated using in vivo, in vitro, and atomic force microscopy experiments.采用体内、体外和原子力显微镜实验验证了纳米载体与内皮细胞的结合的计算模型。
Proc Natl Acad Sci U S A. 2010 Sep 21;107(38):16530-5. doi: 10.1073/pnas.1006611107. Epub 2010 Sep 7.
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Potential role of size and hemodynamics in the efficacy of vascular-targeted spherical drug carriers.载药球囊血管靶向治疗中球囊大小和血流动力学的潜在作用
Biomaterials. 2010 Feb;31(6):1392-402. doi: 10.1016/j.biomaterials.2009.11.007. Epub 2009 Dec 2.
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Emerging nanotechnology-based strategies for the identification of microbial pathogenesis.新兴的基于纳米技术的微生物发病机制鉴定策略。
Adv Drug Deliv Rev. 2010 Mar 18;62(4-5):408-23. doi: 10.1016/j.addr.2009.11.013. Epub 2009 Nov 13.
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Flow dynamics, binding and detachment of spherical carriers targeted to ICAM-1 on endothelial cells.靶向内皮细胞上细胞间黏附分子-1(ICAM-1)的球形载体的流动动力学、结合与脱离
Biorheology. 2009;46(4):323-41. doi: 10.3233/BIR-2009-0544.
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Nanoparticle-based targeted drug delivery.基于纳米颗粒的靶向药物递送。
Exp Mol Pathol. 2009 Jun;86(3):215-23. doi: 10.1016/j.yexmp.2008.12.004. Epub 2009 Jan 7.
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Selectin catch-slip kinetics encode shear threshold adhesive behavior of rolling leukocytes.选择素捕获-滑动动力学编码滚动白细胞的剪切阈值粘附行为。
Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20716-21. doi: 10.1073/pnas.0808213105. Epub 2008 Dec 18.
8
The Role of Glycocalyx in Nanocarrier-Cell Adhesion Investigated Using a Thermodynamic Model and Monte Carlo Simulations.使用热力学模型和蒙特卡洛模拟研究糖萼在纳米载体-细胞黏附中的作用。
J Phys Chem C Nanomater Interfaces. 2007 Nov 1;111(43):15848-15856. doi: 10.1021/jp074514x.
9
The margination propensity of spherical particles for vascular targeting in the microcirculation.球形粒子在微循环中血管靶向的边缘倾向。
J Nanobiotechnology. 2008 Aug 15;6:9. doi: 10.1186/1477-3155-6-9.
10
Shape effects of filaments versus spherical particles in flow and drug delivery.流动和药物递送中长丝与球形颗粒的形状效应
Nat Nanotechnol. 2007 Apr;2(4):249-55. doi: 10.1038/nnano.2007.70. Epub 2007 Mar 25.

动态因素控制载体在血管细胞上的锚定。

Dynamic factors controlling carrier anchoring on vascular cells.

机构信息

Department of Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, USA.

出版信息

IUBMB Life. 2011 Aug;63(8):640-7. doi: 10.1002/iub.475. Epub 2011 Jun 30.

DOI:10.1002/iub.475
PMID:21721099
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3142280/
Abstract

This article reviews experimental and modeling methods for determining the critical roles played by the various factors that control nanocarrier drug delivery to vascular endothelial cells.

摘要

本文综述了实验和建模方法,用于确定控制纳米载体向血管内皮细胞递药的各种因素的关键作用。