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社区中的猪流感疫苗接种计划:可接受性、反应与应对措施

Swine influenza vaccine program in the community: acceptability, reactions and responses.

作者信息

Monto A S, Ross H W

出版信息

Am J Public Health. 1979 Mar;69(3):233-7. doi: 10.2105/ajph.69.3.233.

Abstract

The operation of the national swine influenza immunization program was observed in the community of Tecumseh, Michigan. The purpose was to determine acceptability of a parenteral vaccine intended for the general population. Participation of the residents was excellent. More than 64 per cent of eligibles were vaccinated; this figure resembled that of the rest of the local area, but not the national figures nor a suburban area of Michigan where a similar study was carried out. Sore arm after vaccination was reported most frequently in younger female participants; however, sore arm was accepted as part of the process of vaccination and not considered a reaction by most. Such perceived reactions were not as commonly reported as in the large suburban area. Antibody response to the vaccine was excellent, not only in terms of antibodies to the swine virus itself but also in terms of cross reactive antibodies to the emergent H1N1 (Russian) influenza strain. As a result of the program, many vaccine recipients in the 25 to 49 year age groups are protected against this new epidemic virus.

摘要

在密歇根州蒂康塞社区观察了国家猪流感免疫计划的实施情况。目的是确定一种面向普通人群的注射用疫苗的可接受性。居民的参与度很高。超过64%符合条件的人接种了疫苗;这一数字与当地其他地区相似,但与全国数据以及密歇根州进行类似研究的一个郊区不同。接种疫苗后手臂疼痛在年轻女性参与者中报告最为频繁;然而,手臂疼痛被视为接种过程的一部分,大多数人并不认为这是一种反应。这种可感知的反应不像在大郊区那样常见。疫苗的抗体反应良好,不仅针对猪病毒本身的抗体,而且针对新出现的H1N1(俄罗斯)流感毒株的交叉反应抗体。由于该计划,许多25至49岁年龄组的疫苗接种者对这种新的流行病毒具有免疫力。

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