de Morais Lima Gedson Rodrigues, de Albuquerque Montenegro Camila, de Almeida Cynthia Layse Ferreira, de Athayde-Filho Petrônio Filgueiras, Barbosa-Filho José Maria, Batista Leônia Maria
Laboratory of Pharmaceutical Technology, Department of Pharmaceutical Sciences, Federal University of Paraiba, 58051-970, João Pessoa, PB, Brazil; E-Mails:
Int J Mol Sci. 2011;12(4):2692-749. doi: 10.3390/ijms12042692. Epub 2011 Apr 21.
Inflammation is a complex event linked to tissue damage whether by bacteria, physical trauma, chemical, heat or any other phenomenon. This physiological response is coordinated largely by a variety of chemical mediators that are released from the epithelium, the immunocytes and nerves of the lamina propria. However, if the factor that triggers the inflammation persists, the inflammation can become relentless, leading to an intensification of the lesion. The present work is a literature survey of plant extracts from the South American continent that have been reported to show anti-inflammatory activity. This review refers to 63 bacterial families of which the following stood out: Asteraceae, Fabaceae, Euphorbiaceae, Apocynaceae and Celastraceae, with their countries, parts used, types of extract used, model bioassays, organisms tested and their activity.
炎症是一种与组织损伤相关的复杂过程,无论是由细菌、物理创伤、化学物质、热或任何其他现象引起的。这种生理反应主要由从上皮细胞、免疫细胞和固有层神经释放的多种化学介质协调。然而,如果引发炎症的因素持续存在,炎症可能会持续不断,导致病变加剧。本研究是对南美洲大陆已报道具有抗炎活性的植物提取物的文献综述。该综述涉及63个细菌科,其中以下几个科较为突出:菊科、豆科、大戟科、夹竹桃科和卫矛科,包括其所在国家、使用的部位、提取物类型、模型生物测定、测试的生物体及其活性。