具有抗溃疡活性的美洲大陆植物。

Plants of the American continent with antiulcer activity.

作者信息

Falcão H S, Mariath I R, Diniz M F F M, Batista L M, Barbosa-Filho J M

机构信息

Laboratório de Tecnologia Farmacêutica, Universidade Federal da Paraíba, Cx. Postal 5009, 58051-970 João Pessoa, PB, Brazil.

出版信息

Phytomedicine. 2008 Jan;15(1-2):132-46. doi: 10.1016/j.phymed.2007.07.057. Epub 2007 Sep 29.

Abstract

Peptic ulcer is a chronic and appalling disease. Today, it is dominant among the diseases that affect the world's population. The principal factors causing this disease are inadequate dietetic habits, prolonged use of non-steroidal anti-inflammatory drugs, stress and infection by Helicobacter pylori, in addition to other factors of genetic origin. The present work is a literature survey of plant extracts from the American continent that have been reported to show antiulcer activity. This review refers to 58 plants with their families, parts used, type of extract used, model bioassays and their activity. This work intends to aid the researchers in the study of natural products appropriate to the treatment of stomach and intestinal diseases, in general, and peptic ulcer in particular.

摘要

消化性溃疡是一种慢性且严重的疾病。如今,它在影响全球人口的疾病中占据主导地位。导致这种疾病的主要因素包括饮食习惯不良、长期使用非甾体抗炎药、压力以及幽门螺杆菌感染,此外还有其他遗传因素。本研究是对美洲大陆已报道具有抗溃疡活性的植物提取物的文献综述。该综述涉及58种植物,包括它们所属的科、使用的部位、提取物类型、生物测定模型及其活性。这项工作旨在帮助研究人员研究适用于治疗一般胃肠疾病,特别是消化性溃疡的天然产物。

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