磷酸烯醇式丙酮酸羧激酶在肌肉氨基酸代谢中的作用。
The role of phosphoenolpyruvate carboxykinase in amino acid metabolism in muscle.
作者信息
Newsholme E A, Williams T
出版信息
Biochem J. 1978 Nov 15;176(2):623-6. doi: 10.1042/bj1760623.
Abstract
Starvation or feeding rats on a high-protein diet, valine or isoleucine, but not leucine, increases the activity of muscle phosphoenolpyruvate carboxykinase, but has no effect on NADP+-linked malate dehydrogenase. This suggests that muscle phosphoenolpyruvate carboxykinase is involved in oxidation or conversion of some amino acids to alanine.
摘要
让大鼠饥饿或喂食高蛋白饮食、缬氨酸或异亮氨酸（而非亮氨酸），会增加肌肉磷酸烯醇式丙酮酸羧激酶的活性，但对与NADP⁺相关的苹果酸脱氢酶没有影响。这表明肌肉磷酸烯醇式丙酮酸羧激酶参与了某些氨基酸向丙氨酸的氧化或转化过程。
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