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Plus-strand origin for human immunodeficiency virus type 1: implications for integration.

作者信息

Pullen K A, Champoux J J

机构信息

Department of Microbiology, School of Medicine, University of Washington, Seattle 98195.

出版信息

J Virol. 1990 Dec;64(12):6274-7. doi: 10.1128/JVI.64.12.6274-6277.1990.

Abstract

The start site for human immunodeficiency virus type 1 plus strands within the polypurine tract was mapped by an in vitro analysis to the sequence 5'-ACTG....From this result, it can be inferred that integration of human immunodeficiency virus type 1 must be accompanied by the loss of two base pairs from the polypurine tract-primed long terminal repeat end.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2928/248804/0cd9cfdda091/jvirol00067-0594-a.jpg

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