Public Health Sciences, Karlstad University, Sweden.
Int J Environ Health Res. 2011 Aug;21(4):237-47. doi: 10.1080/09603123.2010.533368. Epub 2011 Jun 16.
Most studies studying dampness as a risk factor for asthma are of a cross-sectional design. The aim of this study was to investigate if the association between moisture-related problems indoor and asthma found in cross-sectional questionnaire data can be confirmed in longitudinal analyses. The Dampness in Building and Health (DBH) study started in 2000 in Värmland, Sweden, with a baseline questionnaire to all children aged 1-5 y (n = 14,077) and five years later a follow-up questionnaire was distributed to children aged 6-8 y (n = 7,509). Moisture-related problems that were associated with asthma in cross-sectional analysis decreased or disappeared in the longitudinal analysis. However, the association between reports of moldy odor in the homes at baseline and incident asthma remained and became stronger. Our results suggest that cross-sectional data showing associations between moisture-related problems in homes and asthma in children partly can be explained by reporting bias.
大多数研究将潮湿作为哮喘的危险因素进行研究，这些研究大多采用横断面设计。本研究旨在调查在横断面问卷调查数据中发现的与室内潮湿相关问题和哮喘之间的关联，是否可以在纵向分析中得到证实。瑞典瓦尔地区于 2000 年开展了建筑与健康中的潮湿问题（DBH）研究，在基线时向所有 1-5 岁儿童（n=14077）发放问卷，5 年后向 6-8 岁儿童（n=7509）发放随访问卷。在横断面分析中与哮喘相关的潮湿相关问题在纵向分析中减少或消失。然而，在家中闻到发霉气味与新发生哮喘之间的关联仍然存在且变得更强。我们的研究结果表明，横断面数据显示家庭潮湿问题与儿童哮喘之间的关联，部分可以通过报告偏倚来解释。
