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Sero-immunity and serologic response to pandemic influenza A (H1N1) 2009 virus in Hong Kong.香港人群对甲型 H1N1 流感病毒的血清学免疫和血清学反应。
J Med Virol. 2010 Nov;82(11):1809-15. doi: 10.1002/jmv.21895.
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Serological survey of 2009 H1N1 influenza in residents of Beijing, China.中国北京居民中 2009 年 H1N1 流感的血清学调查。
Epidemiol Infect. 2011 Jan;139(1):52-8. doi: 10.1017/S0950268810002189. Epub 2010 Sep 21.
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2009 influenza A(H1N1) seroconversion rates and risk factors among distinct adult cohorts in Singapore.2009 年甲型 H1N1 流感在新加坡不同成年人群中的血清转化率和危险因素。
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Serologic survey of pandemic (H1N1) 2009 virus, Guangxi Province, China.中国广西2009年甲型H1N1流感大流行病毒的血清学调查
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Cross-reactive antibody responses to the 2009 pandemic H1N1 influenza virus.对2009年甲型H1N1流感大流行病毒的交叉反应性抗体应答。
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Avian influenza viruses in humans.人类中的禽流感病毒。
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Broad cross-protection against H5N1 avian influenza virus infection by means of monoclonal antibodies that map to conserved viral epitopes.通过靶向保守病毒表位的单克隆抗体实现对H5N1禽流感病毒感染的广泛交叉保护。
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Antigenic profile of avian H5N1 viruses in Asia from 2002 to 2007.2002年至2007年亚洲禽流感H5N1病毒的抗原特征
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未接种流感疫苗人群中流感 A 病毒抗体的血清学调查。

Serological survey of antibodies to influenza A viruses in a group of people without a history of influenza vaccination.

机构信息

National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Sciences, Xiamen University, Xiamen, Fujian Province, China.

出版信息

Clin Microbiol Infect. 2011 Sep;17(9):1347-9. doi: 10.1111/j.1469-0691.2011.03538.x. Epub 2011 Jul 13.

DOI:10.1111/j.1469-0691.2011.03538.x
PMID:21749549
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3166400/
Abstract

A serological survey for antibodies to influenza viruses was performed in China on a group of people without a history of influenza vaccination. Using the haemagglutination inhibition (HI) assay, we found seropositivity rates for seasonal H3N2 to be significantly higher than those for seasonal H1N1. Samples positive for antibodies to the pandemic (H1N1) 2009 virus increased from 0.6% pre-outbreak to 4.5% (p <0.01) at 1 year post-outbreak. Interestingly, HI and neutralization tests showed that 1.4% of people in the group have antibodies recognizing H9N2 avian influenza viruses, suggesting that infection with this subtype may be more common than previously thought.

摘要

在中国，我们对一组没有流感疫苗接种史的人群进行了血清抗体流感病毒检测。采用血凝抑制（HI）试验，我们发现季节性 H3N2 的血清阳性率明显高于季节性 H1N1。大流行（H1N1）2009 病毒抗体阳性样本在疫情爆发后 1 年从 0.6%上升到 4.5%（p<0.01）。有趣的是，HI 和中和试验显示，该人群中有 1.4%的人具有识别 H9N2 禽流感病毒的抗体，这表明感染这种亚型可能比之前认为的更为常见。