Buff E M, Petruk S F, Gerasimova T I
Genetika. 1993 Nov;29(11):1784-92.
A number of mutations in different Drosophila loci resulted from the relationship between hobo and stalker mobile elements. In this investigation an insertion from the parential white mutation-waG-was cloned. And the Doc element, that is the reason of the mutation, is not moving in the observed instability system. But transpositions of the copia-like elements (e.g. mdg1, 2, 3 and copia) were shown in this system. A cases of chromosomal rearrangements and abnormal recombination in compound with transpositions of different mobile elements were found. Thus, the system of instability could be explained in terms of universal mechanism which involved both transpositions and recombinations phenomena.
果蝇不同基因座上的一些突变是由hobo和stalker移动元件之间的关系导致的。在这项研究中,克隆了来自亲本白色突变体waG的一个插入片段。导致该突变的Doc元件在观察到的不稳定系统中并不移动。但在这个系统中显示出类copia元件(如mdg1、2、3和copia)的转座。发现了与不同移动元件转座相关的染色体重排和异常重组的情况。因此,不稳定系统可以用涉及转座和重组现象的普遍机制来解释。