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[黑腹果蝇中黄色基因增强子与黄色基因之间的相互作用]

[Interaction between the enhancers of yellow and the yellow gene in Drosophila melanogaster].

作者信息

Kozitsina M V, Abramova N A, Georgiev P G

出版信息

Genetika. 1992 Nov;28(11):59-67.

PMID:1337532
Abstract

Earlier, mutations at six loci designated enhancers of yellow (e(y)1-6) were obtained in the system of prolonged instability, where transpositions of Stalker mobile element occur. These mutations decrease pigmentation of the cuticle in a number of alleles. In the present work, genetic analysis of the mechanism of action of e(y)1u1, e(y)3u1 and newly described e(y)7u1 mutations on the yellow locus expression was conducted. The data are obtained proving that the enhancers of yellow 1 and 3 control transcription of the yellow locus. At the same time, the interaction of here described gene e(y)7 with the yellow gene is likely to occur at the level of protein products.

摘要

早些时候,在 stalker 移动元件发生转座的长期不稳定系统中,获得了六个被命名为黄色增强子(e(y)1 - 6)的位点的突变。这些突变在多个等位基因中降低了表皮的色素沉着。在本研究中,对 e(y)1u1、e(y)3u1 和新描述的 e(y)7u1 突变对黄色位点表达的作用机制进行了遗传分析。获得的数据证明黄色增强子 1 和 3 控制黄色位点的转录。同时,这里描述的基因 e(y)7 与黄色基因的相互作用可能发生在蛋白质产物水平。

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