Ellis Trevor K, Clayton Stephen M, Powell Douglas R, Taylor Richard W
University of Oklahoma, Department of Chemistry and Biochemistry, 101 Stephenson Pkwy, Norman, OK 73019-5251, USA.
Acta Crystallogr Sect E Struct Rep Online. 2011 Jun 1;67(Pt 6):o1533. doi: 10.1107/S1600536811018873. Epub 2011 May 28.
The macrobicyclic title compound, C(23)H(35)N(3)O(8)S, contains two tertiary amide bridgehead N atoms and a toluene-sulfonamide N atom in the center of the five-atom bridging strand. The mol-ecule has a central cavity that is defined by the 18-membered ring identified by the N(2)O(4) donor atom set and two 15-membered rings with N(3)O(2) donor atom sets. The toluene-sulfonamide N atom adopts an exo orientation with respect to the central cavity, and the tosyl group is oriented on one side of the aza-bridging strand that connects the bridgehead N atoms.
大环标题化合物C(23)H(35)N(3)O(8)S在五元桥连链的中心含有两个叔酰胺桥头氮原子和一个甲苯磺酰胺氮原子。该分子有一个中心腔，由由N(2)O(4)供体原子集确定的18元环和两个具有N(3)O(2)供体原子集的15元环所界定。甲苯磺酰胺氮原子相对于中心腔采取外向取向，并且甲苯磺酰基位于连接桥头氮原子的氮杂桥连链的一侧。
