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结核分枝杆菌复合群检测用 TB Ag MPT64 快速检测试剂的评估。

Evaluation of the TB Ag MPT64 Rapid test for the identification of Mycobacterium tuberculosis complex.

机构信息

Institute of Tropical Medicine, Antwerp, Belgium.

出版信息

Int J Tuberc Lung Dis. 2011 May;15(5):703-5. doi: 10.5588/ijtld.10.0474.

DOI:10.5588/ijtld.10.0474
PMID:21756526
Abstract

Rapid identification of Mycobacterium tuberculosis complex in cultured samples is important for starting appropriate treatment. We evaluated the performance of the TB Ag MPT64 Rapid test directly from 131 BACTEC MGIT 960 culture-positive samples: 113 were identified as M. tuberculosis complex and 18 as non-tuberculous mycobacteria. The sensitivity and specificity of the TB Ag MPT64 Rapid test were respectively 96.5% and 100% compared to the polymerase chain reaction. The overall concordance of the TB Ag MPT64 Rapid test was 969%. The TB Ag MPT64 Rapid test is easy, sensitive, and does not require a high level of skill or specific equipment.

摘要

快速鉴定培养样本中的结核分枝杆菌复合体对于开始适当的治疗非常重要。我们评估了 TB Ag MPT64 快速检测法直接检测 131 份 BACTEC MGIT 960 培养阳性样本的性能:113 份被鉴定为结核分枝杆菌复合体,18 份为非结核分枝杆菌。与聚合酶链反应相比,TB Ag MPT64 快速检测法的灵敏度和特异性分别为 96.5%和 100%。TB Ag MPT64 快速检测法的总符合率为 96.9%。TB Ag MPT64 快速检测法简便、敏感,且不需要高水平的技能或特定设备。

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