Department of Chest Disease, Baskent University Medical and Research Center, Adana, Turkey.
Ann Thorac Med. 2011 Jul;6(3):131-6. doi: 10.4103/1817-1737.82443.
Bronchiectasis continues to be one of the major causes of morbidity and mortality in developing countries, with a probably underestimated higher prevalence than in developed countries.
To assess the clinical profile of adult patients with bronchiectasis.
We retrospectively reviewed the clinical, radiologic, and physiologic findings of 304 patients with bronchiectasis confirmed by high-resolution computed tomography.
Mean age of participants (45.7% males, 54.3% females) was 56 ± 25 years and 65.8% of them were lifetime non-smokers. Most common identified causes of bronchiectasis were childhood disease (22.7%), tuberculosis (15.5%), and pneumonia (11.5%). The predominant symptoms were productive cough (83.6%), dyspnea (72%), and hemoptysis (21.1%). The most common findings on chest examination were crackles (71.1%) and rhonchi (28.3%). Types of bronchiectasis were cylindrical in 47%, varicose in 9.9%, cystic in 45.1%, and multiple types in 24.3%. Involvement was multilobar in 75.3% and bilateral in 62.5%. Of 274 patients, 20.8% displayed normal pulmonary function test results, whereas 47.4%, 8% and 23.7% showed obstructive, restrictive, and mixed pattern, respectively. Patients with cystic disease had a higher frequency of hemoptysis (42%) and a greater degree of functional impairment, compared to other types.
In patients with bronchiectasis from southern Turkey, generally presenting with recurrent productive cough, hemoptysis, dyspnea, and persistent bibasilar rales, the etiology remains mainly idiopathic. Post-infectious bronchial destruction is one of the major identified underlying pathological processes. The clinical picture and the deterioration of the pulmonary function test might be more severe in patients with cystic type bronchiectasis.
支气管扩张症仍然是发展中国家发病率和死亡率的主要原因之一，其患病率可能高于发达国家，但被低估。
评估成人支气管扩张症患者的临床特征。
我们回顾性分析了 304 例经高分辨率计算机断层扫描（HRCT）证实的支气管扩张症患者的临床、放射学和生理学资料。
参与者的平均年龄（45.7%为男性，54.3%为女性）为 56±25 岁，65.8%为终身不吸烟者。支气管扩张症最常见的病因是儿童时期疾病（22.7%）、结核病（15.5%）和肺炎（11.5%）。最常见的症状是咳痰（83.6%）、呼吸困难（72%）和咯血（21.1%）。胸部检查最常见的体征是湿啰音（71.1%）和喘鸣音（28.3%）。支气管扩张症的类型为柱状型 47%、静脉曲张型 9.9%、囊状型 45.1%和多发型 24.3%。多叶受累 75.3%，双侧受累 62.5%。274 例患者中，20.8%的肺功能检查结果正常，47.4%、8%和 23.7%分别表现为阻塞性、限制性和混合性模式。与其他类型相比，囊性病变患者咯血（42%）和功能损害更常见。
在来自土耳其南部的支气管扩张症患者中，通常表现为反复出现的咳痰、咯血、呼吸困难和持续的双肺底湿啰音，病因主要为特发性。感染后支气管破坏是主要的潜在病理过程之一。囊性支气管扩张症患者的临床症状和肺功能恶化可能更严重。
