Singh Priyanka, Katoch C D S, Vardhan Vasu, Chopra Manu, Singh Sarvinder, Ahuja Nitin
Department of Pulmonary Medicine, Army Hospital (Research and Referral), New Delhi, India.
Department of Pulmonary Medicine, Army Institute of Cardio-Thoracic Sciences, Pune, Maharashtra, India.
Lung India. 2021 Nov-Dec;38(6):545-551. doi: 10.4103/lungindia.lungindia_707_20.
Bronchiectasis is a common respiratory disease which has significant morbidity and mortality. Health-related quality of life scores are not routinely used for the assessment of bronchiectasis. The present study was undertaken with an aim to assess the clinical profile and functional impairment using spirometry in patients with bronchiectasis and to co-relate functional impairment with their St. George's Respiratory Questionnaire (SGRQ) score.
This was a cross-sectional study carried out on 102 patients of bronchiectasis. All patients were assessed for clinical profile, spirometry, and SGRQ scores. Forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC) and FEV1/FVC were measured and compared with SGRQ scores. Data analysis was done using SPSS version 20.0 and MS-Excel.
Obstruction was found in 62.7% and significant bronchodilator reversibility was observed in 30.4%. All spirometry parameters individually and combined showed a negative co-relation which was stastically significant (P < 0.001). Best co-relation was with FEV1 r = -0.809; symptom score, r = -0.821; activity score, r= -0.849; impact score and r = -0.873 total score. FVC% versus symptoms score r = -0.735; activity score r = -0.729, impacts score r = -0.778; total score r = -0.792. FEV1/FVC versus symptoms score r = -0.227, activity score r = -0.278, impacts score r = -0.263, total score r = -0.274.
SGRQ scores have shown good correlation with functional impairment. It can be used as a modality to evaluate health status of patient in resource constraint settings.
支气管扩张是一种常见的呼吸系统疾病，具有较高的发病率和死亡率。与健康相关的生活质量评分未常规用于支气管扩张的评估。本研究旨在通过肺功能测定评估支气管扩张患者的临床特征和功能损害，并将功能损害与圣乔治呼吸问卷（SGRQ）评分相关联。
这是一项对102例支气管扩张患者进行的横断面研究。所有患者均接受临床特征、肺功能测定和SGRQ评分评估。测量第1秒用力呼气容积（FEV1）、用力肺活量（FVC）和FEV1/FVC，并与SGRQ评分进行比较。使用SPSS 20.0版和MS-Excel进行数据分析。
62.7%的患者存在阻塞，30.4%的患者观察到显著的支气管扩张剂可逆性。所有肺功能测定参数单独或综合显示均呈负相关，具有统计学意义（P < 0.001）。最佳相关性为FEV1，r = -0.809；症状评分，r = -0.821；活动评分，r = -0.849；影响评分，r = -0.873；总分。FVC%与症状评分，r = -0.735；活动评分，r = -0.729；影响评分，r = -0.778；总分，r = -0.792。FEV1/FVC与症状评分，r = -0.227；活动评分，r = -0.278；影响评分，r = -0.263；总分，r = -0.274。
SGRQ评分与功能损害显示出良好的相关性。它可作为在资源有限环境中评估患者健康状况的一种方式。
