Control of Exotic and Emerging Animal Diseases, Montpellier, France.
Emerg Infect Dis. 2011 Jul;17(7):1223-31. doi: 10.3201/eid1707.101216.
Interest in peste des petits ruminants virus (PPRV) has been stimulated by recent changes in its host and geographic distribution. For this study, biological specimens were collected from camels, sheep, and goats clinically suspected of having PPRV infection in Sudan during 2000-2009 and from sheep soon after the first reported outbreaks in Morocco in 2008. Reverse transcription PCR analysis confirmed the wide distribution of PPRV throughout Sudan and spread of the virus in Morocco. Molecular typing of 32 samples positive for PPRV provided strong evidence of the introduction and broad spread of Asian lineage IV. This lineage was defined further by 2 subclusters; one consisted of camel and goat isolates and some of the sheep isolates, while the other contained only sheep isolates, a finding with suggests a genetic bias according to the host. This study provides evidence of the recent spread of PPRV lineage IV in Africa.
人们对小反刍兽疫病毒（PPRV）的兴趣受到其宿主和地理分布近期变化的刺激。在这项研究中，从 2000 年至 2009 年苏丹临床疑似感染 PPRV 的骆驼、绵羊和山羊，以及 2008 年摩洛哥首次报告暴发后不久的绵羊采集生物标本。反转录 PCR 分析证实 PPRV 在苏丹广泛分布，并在摩洛哥传播。对 32 份 PPRV 阳性样本的分子分型提供了亚洲谱系 IV 传入和广泛传播的有力证据。该谱系进一步分为 2 个子群；一个由骆驼和山羊分离株和一些绵羊分离株组成，而另一个只包含绵羊分离株，这一发现表明根据宿主存在遗传偏向。本研究提供了 PPRV 谱系 IV 在非洲近期传播的证据。
