Tokuyama Yasuharu, Osada Shinji, Sanada Yuichi, Takahashi Takao, Yamaguchi Kazuya, Yoshida Kazuhiro
Department of Surgical Oncology, Graduate School of Medicine, Gifu University, Gifu, Japan.
Rare Tumors. 2011 Apr 4;3(2):e14. doi: 10.4081/rt.2011.e14.
Mucinous cystic neoplasms (MCNs) make up a morphologic family of similar appearing tumors arising in the ovary and various extraovarian organs such as pancreas, hepatobiliary tract and mesentery. MCNs of the pancreas occur almost exclusively in women. Here, we report a rare case of MCN in a male patient. A 39-year-old man was admitted to our hospital with the chief complaint of back pain. Abdominal computed tomography revealed a multilocular cyctic mass 6.3 cm in diameter in the pancreatic tail. In addition, the outer wall and septae with calcification were demonstrated in the cystic lesion. On magnetic resonance imaging , the cystic fluid had low intensity on T1-weighted imaging and high intensity on T2-weighted imaging. Endoscopic retrograde cholangio-pancreatography (ERCP) showed neither communication between the cystic lesion and the main pancreatic duct nor encasement of the main pancreatic duct. Endoscopic ultrasonography revealed neither solid component nor thickness of the septae in the cystic lesion. Consequently, we performed distal pancreatectomy with splenectomy under the diagnosis of cystic neoplasia of the pancreas. Histopathologically, the cystic lesion showed two distinct component: an inner epithelial layer and an outer densely cellular ovarian-type stromal layer. Based on these findings, the cystic lesion was diagnosed as MCN.
黏液性囊性肿瘤（MCNs）是一组形态学上相似的肿瘤，发生于卵巢以及胰腺、肝胆管和肠系膜等各种卵巢外器官。胰腺MCNs几乎仅见于女性。在此，我们报告一例男性患者的罕见胰腺MCNs病例。一名39岁男性因背痛主诉入院。腹部计算机断层扫描显示胰腺尾部有一个直径6.3 cm的多房囊性肿块。此外，囊性病变的外壁和分隔有钙化表现。磁共振成像显示，囊性液体在T1加权成像上呈低信号，在T2加权成像上呈高信号。内镜逆行胰胆管造影（ERCP）显示囊性病变与主胰管之间无相通，主胰管也未受压。内镜超声检查显示囊性病变内无实性成分，分隔也不厚。因此，我们在胰腺囊性肿瘤的诊断下实施了远端胰腺切除术加脾切除术。组织病理学检查显示，囊性病变有两个不同的成分：内层上皮层和外层富含细胞的卵巢型间质层。基于这些发现，该囊性病变被诊断为MCN。
