Latvian Institute of Organic Synthesis, Aizkraukles 21, LV-1006, Riga, Latvia.
Org Lett. 2011 Aug 19;13(16):4324-7. doi: 10.1021/ol201665c. Epub 2011 Jul 20.
A mild, room-temperature Pd-catalyzed acetoxylation of pyrroles with phenyliodonium acetate is described. The acetoxylation was found to proceed via the initial formation of pyrrolyl(phenyl)iodonium acetates, which were converted to acetoxypyrroles in the presence of Pd(OAc)(2). The acetoxylation could also be carried out as a one-pot sequential procedure without the isolation of the intermediate iodonium salts.
描述了一种温和、室温下的钯催化吡咯与醋酸苯碘翁盐的乙酰氧基化反应。研究发现，乙酰氧基化反应是通过初始形成吡咯基（苯基）碘翁醋酸盐进行的，在 Pd(OAc)(2) 的存在下，这些盐转化为乙酰氧基吡咯。乙酰氧基化反应也可以在不分离中间碘翁盐的情况下一锅连续进行。
