Section of Gastroenterology, Department of Medicine, Southern Arizona VA Health Care System, Tucson, Arizona 85723-0001, USA.
Dis Esophagus. 2012 Feb;25(2):89-101. doi: 10.1111/j.1442-2050.2011.01225.x. Epub 2011 Jul 21.
Noncardiac chest pain (NCCP) is a common and challenging clinical problem. It is estimated that more than 70 million Americans (23% of the population) suffer from this condition yearly. Patients with NCCP represent a diagnostic dilemma. Their chest pain is often indistinguishable from cardiac pain leading to extensive and expensive evaluations. Once coronary artery disease and other cardiac and pulmonary sources of chest pain are excluded, patients are frequently referred to gastroenterologists to look primarily for esophageal sources of pain. A variety of diagnostic tests are available to the practicing clinician to identify the origin of pain, including ambulatory pH testing, esophageal motility, upper endoscopy, provocative testing and even therapeutic trials.
非心因性胸痛（NCCP）是一种常见且具有挑战性的临床问题。据估计，每年有超过 7000 万美国人（占总人口的 23%）患有这种疾病。NCCP 患者构成了诊断难题。他们的胸痛常常与心脏疼痛难以区分，导致广泛而昂贵的评估。一旦排除了冠状动脉疾病和其他心脏和肺部引起胸痛的原因，患者通常会被转介给胃肠病学家，主要寻找食管疼痛的来源。临床医生可使用多种诊断测试来确定疼痛的来源，包括动态 pH 测试、食管动力、上内窥镜检查、激发试验甚至治疗试验。
