Bäckman E, Henriksson K G
Department of Clinical Neurophysiology, University Hospital, Linköping, Sweden.
J Intern Med. 1990 Dec;228(6):577-81. doi: 10.1111/j.1365-2796.1990.tb00282.x.
Fifteen patients with myotonic dystrophy, seven men and eight women, of age range 15-55 years, were treated with sodium selenite and vitamin E for 2 years. The patients were examined using a number of tests to assess muscle force and function at the start of the treatment period and 6, 12 and 24 months thereafter. Myotonia gives an increased relaxation time. The latter was measured in the adductor pollicis. There was a significant decrease in half relaxation time before treatment compared with the values during treatment. In summary, the results indicate that selenium and vitamin E therapy may have an effect on myotonia. The effects of treatment on motor functions were minimal, and overall motor performance was not improved.
15例患有强直性肌营养不良的患者（7名男性和8名女性，年龄在15至55岁之间）接受了亚硒酸钠和维生素E治疗，为期2年。在治疗期开始时以及之后的6个月、12个月和24个月，使用多项测试对患者进行检查，以评估肌肉力量和功能。肌强直会使放松时间延长。后者在内收拇肌中进行测量。与治疗期间的值相比，治疗前的半放松时间显著缩短。总之，结果表明硒和维生素E疗法可能对肌强直有影响。治疗对运动功能的影响很小，整体运动表现并未改善。
