Endocannabinoids: an appetite for fat.
作者信息
Di Marzo Vincenzo
机构信息
Endocannabinoid Research Group, Institute of Biomolecular Chemistry, Consiglio Nazionale delle Ricerche, 80078 Pozzuoli, Italy.
出版信息
Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12567-8. doi: 10.1073/pnas.1109567108. Epub 2011 Jul 21.
Abstract
摘要
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Trends Neurosci. 2011 Jan;34(1):31-40. doi: 10.1016/j.tins.2010.10.001. Epub 2010 Oct 28.
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Increment of hypothalamic 2-arachidonoylglycerol induces the preference for a high-fat diet via activation of cannabinoid 1 receptors.下丘脑 2-花生四烯酸甘油增加通过激活大麻素 1 受体诱导高脂肪饮食偏好。
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The endocannabinoid 2-arachidonoyl-glycerol controls odor sensitivity in larvae of Xenopus laevis.内源性大麻素 2-花生四烯酰甘油控制非洲爪蟾幼虫的气味敏感性。
J Neurosci. 2010 Jun 30;30(26):8965-73. doi: 10.1523/JNEUROSCI.4030-09.2010.
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Taste preference for fatty acids is mediated by GPR40 and GPR120.脂肪酸的味觉偏好由 GPR40 和 GPR120 介导。
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Peripheral endocannabinoid dysregulation in obesity: relation to intestinal motility and energy processing induced by food deprivation and re-feeding.肥胖症外周内源性大麻素系统失调：与饥饿和再喂养诱导的肠道运动和能量处理的关系。
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Activating parabrachial cannabinoid CB1 receptors selectively stimulates feeding of palatable foods in rats.激活臂旁核大麻素CB1受体可选择性刺激大鼠对美味食物的摄取。
J Neurosci. 2008 Sep 24;28(39):9702-9. doi: 10.1523/JNEUROSCI.1171-08.2008.
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Regulation, function, and dysregulation of endocannabinoids in models of adipose and beta-pancreatic cells and in obesity and hyperglycemia.内源性大麻素在脂肪细胞和β胰腺细胞模型以及肥胖症和高血糖症中的调节、功能及调节异常
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