National Institute for Working Life, Risk Assessment Group, Box 210, SE-171 77 Stockholm, Sweden.
Environ Toxicol Pharmacol. 2005 May;19(3):511-6. doi: 10.1016/j.etap.2004.12.057.
Styrene exposure and color vision for 108 workers (21-65 years) was studied at Swedish reinforced plastic plants. Acute exposure was measured at work. Data on past exposures and personal background data were collected by questionnaire. Current exposure varied between 0.3 and 96mg/m(3). Cumulative past exposures varied from 18 to 4455mg years/m(3), and an index of lifetime weighted average exposure (LWAE) varied from 5 to 129mg/m(3). Color vision was tested using the Lanthony D15 desaturated panel binocularly without prior training in conditions with ample light (1400lx). Color vision was slightly correlated to LWAE (r=0.188, p=0.052). Workers were divided into two exposure groups according to LWAE. Analyses of variance revealed effects on the Vingrys' color vision confusion index (F=6.04; p=0.016) and total error (F=6.296; p=0.014). This study thus indicates that styrene exposure even at levels below the current Swedish OEL of 20mg/m(3) may affect color vision negatively.
在瑞典增强塑料工厂对 108 名(21-65 岁)工人的苯乙烯暴露和色觉进行了研究。在工作时测量急性暴露。通过问卷调查收集了过去暴露和个人背景数据。目前的暴露量在 0.3 至 96mg/m(3)之间变化。过去的累积暴露量从 18 至 4455mg 年/m(3)不等,终生加权平均暴露指数(LWAE)从 5 至 129mg/m(3)不等。使用 Lanthony D15 去饱和面板在充足光线条件下(1400lx)进行双眼色觉测试,无需事先进行训练。色觉与 LWAE 有轻微相关性(r=0.188,p=0.052)。根据 LWAE,工人被分为两组暴露组。方差分析显示对 Vingrys 色觉混淆指数(F=6.04;p=0.016)和总误差(F=6.296;p=0.014)有影响。因此,这项研究表明,即使在当前瑞典 20mg/m(3)的 OEL 以下的水平下,苯乙烯暴露也可能对色觉产生负面影响。