Neuroscience Center, Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.
Trends Biotechnol. 2011 Dec;29(12):624-33. doi: 10.1016/j.tibtech.2011.06.010. Epub 2011 Jul 23.
Application of bioluminescence imaging has increased tremendously in the past decade and has significantly contributed to core conceptual advances in biomedical research. This technology provides valuable means for monitoring of different biological processes in immunology, oncology, virology and neuroscience. In this review, we discuss current trends in bioluminescence and its application in different fields with an emphasis on cancer research.
生物发光成像是过去十年中应用增长最快的技术之一,为生物医学研究的核心概念进展做出了重大贡献。该技术为监测免疫学、肿瘤学、病毒学和神经科学中的不同生物学过程提供了有价值的手段。在这篇综述中,我们讨论了生物发光的当前趋势及其在不同领域的应用,重点是癌症研究。