用于体内视网膜成像的光声检眼镜：现状与展望
Photoacoustic ophthalmoscopy for in vivo retinal imaging: current status and prospects.
作者信息
Zhang Hao F, Puliafito Carmen A, Jiao Shuliang
机构信息
Department of Ophthalmology, Keck School of Medicine, University of Southern California, 1450 San Pablo, Los Angeles, CA 90033, USA.
出版信息
Ophthalmic Surg Lasers Imaging. 2011 Jul;42 Suppl(0):S106-15. doi: 10.3928/15428877-20110627-10.
Abstract
Photoacoustic ophthalmoscopy (PAOM) is a new retinal imaging technology that offers the unique capability to measure optical absorption in the retina. Because PAOM is compatible with optical coherence tomography, scanning laser ophthalmoscopy, and autofluorescence imaging, registered multimodal images can be acquired from a single device at comparable resolution for comprehensive anatomic and functional retinal characterizations. Therefore, PAOM is anticipated to have applications in both research and clinical diagnosis of many blinding diseases. The authors explain the basic principles of the photoacoustic effect and imaging. Then, different types of photoacoustic microscopy are introduced and compared. Finally, the current status of photoacoustic imaging in animal eyes is presented and the prospects of future development of PAOM are suggested.
摘要
光声眼科检眼镜（PAOM）是一种新型视网膜成像技术，具有测量视网膜光吸收的独特能力。由于PAOM与光学相干断层扫描、扫描激光检眼镜和自体荧光成像兼容，因此可以从单个设备以可比分辨率获取注册的多模态图像，用于全面的视网膜解剖和功能特征描述。因此，预计PAOM在许多致盲疾病的研究和临床诊断中都有应用。作者解释了光声效应和成像的基本原理。然后，介绍并比较了不同类型的光声显微镜。最后，介绍了光声成像在动物眼中的现状，并提出了PAOM未来发展的前景。
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