University of Southampton, Infection, Inflammation and Immunity Division, School of Medicine, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD, UK.
Nat Rev Neurosci. 2011 Jul 27;12(9):539-44. doi: 10.1038/nrn3087.
Chronic fatigue syndrome (CFS) is a debilitating illness that affects many people. It has been marred by controversy, from initial scepticism in the medical community about the existence of the condition itself to continuing disagreements--mainly between some patient advocacy groups on one side, and researchers and physicians on the other--about the name for the illness, its aetiology, its pathophysiology and the effectiveness of the few currently available treatments. The role of the CNS in the disease is central in many of these discussions. Nature Reviews Neuroscience asked four scientists involved in CFS research about their views on the condition, its causes and the future of research aimed at improving our understanding of this chronic illness.
慢性疲劳综合征(CFS)是一种使人虚弱的疾病,影响了许多人。它一直备受争议,从医学界最初对这种疾病本身的存在持怀疑态度,到目前为止,一直存在着持续的分歧——主要是一些患者权益团体一方,以及研究人员和医生另一方,他们对疾病的名称、病因、病理生理学以及目前为数不多的有效治疗方法存在分歧。中枢神经系统(CNS)在这些讨论中起着核心作用。《自然评论神经科学》采访了四位参与 CFS 研究的科学家,询问他们对这种慢性疾病的看法、病因以及未来旨在增进我们对这种慢性疾病的理解的研究。